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pharm cardio # 2
ch. 22
| drug | moa, ix, se |
|---|---|
| lidocaine (Xylocaine) class | class IB antidysrhythmic |
| lidocaine (Xylocaine) MOA | exerts effects on the conduction system of the hearmaking it difficult for the ventricles to develop dysrhthmia=raises the ventricular fibrillation threshhold. |
| lidocaine (Xylocaine) SE | SIDE EFFECTS cns toxicities such as twitches, convultions,and confusion; respiratory depression or cardiac arrest, and the cardiovascular effect of hyptoention, bradycardia and dysrythemia |
| lidocaine (Xylocaine) MOA | blocks sodium channels |
| lidocaine (Xylocaine) MOA Vaughn WIlliams classification | blockade of sodium channel, accelarate repolarization, decreas APD ( action potential deplorization) |
| amiodarone (cordarone) class | Class III |
| amiodarone (cordarone) MOA | prolong the ERP (effective refractory period) |
| amiodarone (cordarone) MOA | control dysrythmia by inhibiting repolarization and markedly prolong refractoriness and the APD |
| amiodarone (cordarone) MOA | blocks both alpha and beta adrenergic receptors of the SNS. |
| amiodarone (cordarone) indication | ventricular tachycardia |