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CV Pathology

CV Pathology: Leech Lectures

QuestionAnswer
What is the most common congenital heart malformation ventricular septal defect
What is the second most common congenital heart malformation atrial septal defect
True or False: Congenital heart disease is caused solely by genetic influence False: Strong correlations exist between siblings, but enviornmental factors still come into play
Why is thalidomide important known teratogen, causes congenital heart problems
When is the critcal window in development 3-8 weeks
Which type of shunt is more common L -> R or R -> L L -> R
Which shunt would cause cyanosis and emboli from venous ciculation to enter systemic circulation R -> L
What is the danger behind a L->R shunt becoming R->L Signifigant pulmonary hypertension can develop and be IRREVERSIBEL
What are the number one cause of CHILDHOOD heart disease shunts
What cardiac myopathy woudl cause digital clubbing and blood deficencies Shunts
True or False: Obstructive myopathies usually cause cyanosis FALSE
What are the three atrial septal defects in order of occurance Secundum (Foreman ovale), Primum (Low in septum), Sinus Venosum (where SVC enters)
Which type of defect is usually silent until adulthood Atrial Septal L-->R shunts
Ventricular septal defects are often associated with what other abonormality tetralogy of Fallot
Where do 90% of ventricular septal defects occur in the membranous material next to the aortic valve
True or False: 85-90% of PAD occurs as an isolated incident true
What is a common presentation in a L-->R shunt that is finally picked up in adulthood Right HEart failure or pulmonary hypertension
Which defect has a machine like sound to it PDA
What are the requirements/components of Tetrolagy of Fallot Ventircular septal defect. Overriding Aorta. Right ventricular Hypertrophy. Pulmonic Stenosis
What component of the Tetrology of Fallot determines severity Pulmonary Stenosis
In Great Vessel transposition, what is the main determining factor of prognosis How well the R. Ventricle can pump and whether there is sufficent PAD occuring
What myopathy occurs when the spiral ridges fail to decend trunctus arteriosis
What always accompanies a trunctus arteriosus Venticular septal defect
What malformation cuases one vessel to recieve blood from both ventricles trunctus arteriosis
With which R-->L shunt disrder do you have r. ventricular hyoplasia and cyanosis from birth Tricuspid Atresia
cardimegaly due to chronic pressure in the left ventricle can cause what Coarctation of the aorta
Where do most coactations in the aorta take place ust distal to the ductus or ligamentum arteriosus
When coarctation develops here, it is usually asymptomatic unless severe postductal
Does collateral flow around a coarctation that is post ductal usually develop yes
What can occur around a coarctation that can lead to or predispose someone to athlerosclerosis Turbulent blood flow
In what condition would you see right ventricular hypoplasticity with an ASD and PDA Pulmonic valve atresia
True or False: Neonates are capable of surviving a complete aortic valve atreia FALSE
Which type of shunting takes place in a truncus arteriosus R-->L
What must be present for a trunus arteriosus to occur VSD
What must be presnet for survival in a transposition of Great Vessels VSD or ASD with PSA (R-->L shunting)
Ishemic Heart disease makes up what % of cardiac deaths 80%
Angina, syncope and CHF are all clinical signs of what Degenerative Calcific Aortic Valve disease
At what age do people with degenerative calcific aortic valve disease have symptoms 70-80
What valve is prone to NOT get infective endocarditis when it becomes clacified Mitral
Which valve, when calcifed, will present with regurgitation with secondary arthymias Mitral
Prolase of the mitral valve may be secondary to abnormalities in which tissue type Marfans
In what age range does mitral valve prolapse occur 20-40
A MIDSYSTOLIC CLICK, with dyspnea, fatigue, phsychiatic problems and chest pain may be caused by what mitral valve prolapse
Elogated or ruptured chordae tendinea would be a finding in which disorder mitral valve prolapse
How is endocarditis diagnosed blood culture
Where do emboli from endocarditis move to spleen, kidney, brain and heart
Vegetations present on one or more vlaves would clue you into endocarditis
erosions or perforations are indicative of what type of endocarditis acute
What organism is usually the cause of endocarditis Staph
Non-bacterial thrombi are seen in patients suffering from what? Cancer, any condtion leaving them bed-ridden with a hypercoaguable state
Do non-bacterial thrmobi produce inflammation or valve damage Nope
mitral and tricuspid fibrinoid necrosis, mucoid degeneration, and small/fibrinous sterile vegetations on leaflets are seen in which disease Endocarditis via SLE
Vegetations from SLE endocardidtis have a tendency to embolize, true or false false
What are the two types of artificial valves Mechanical and bioprothestic (animal)
What percentage of patients experience endocarditis due to vlave replacement 5%
valve occulsion due to over growth and hemolysis are complications due to what valve replacement
You suspect endocarditis, but upon examination you find fibrinoid necrosis and mucoid degeneration... what did this patient have SLE
What is the recommmended HDL for males/females > 35/45
Who's more likely to develop athlerosclerosis, men or women MEN
The pooling/damaging effect of blood on the low pressure of a valve is refered to as... Venturi Effect
Onionskin appearance arteriolosclerosis
Ischemia without infarct is definitive of which disease angina pectoris (stable, unstable, prinzmetal)
What are 90% of transmural MI's caused by 90% occulsion in the coronary arteries
Created by: lowryc
 

 



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