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Drug profiles
atrovent, nos, narcan, verapamil, compazine
| Question | Answer |
|---|---|
| Compazine GENERIC NAME | Prochlorperazine |
| Compazine BRAND NAME | Compazine |
| Compazine CLASS | Antiemetic, antipsychotic |
| Compazine MECHANISM OF ACTION | Alters the affects of dopamine in the CNS. Possesses significant anticholinergic and alpha-adrenergic blocking activity. |
| Compazine INDICATIONS | N/V, psychoses, and anxiety. |
| Compazine CONTRAINDICATIONS | Narrow-angle glaucoma, liver or cardiovascular disease, children < 2 years. |
| Compazine ADVERSE REACTIONS | Sedation, blurred vision, ECG changes, hypotension, tachycardia |
| Compazine INCOMPATABILITIES/DRUG INTERACTIONS | Additive hypotension with antihypertensives, nitrates, or acute ingestion of alcohol. |
| Compazine DOSE/ROUTE Adult Antiemetic, Antipsychotic, and Antianxiety IV | 2.5-10mg not to exceed 40mg day |
| Compazine ONSET OF ACTION | rapid |
| Compazine PEAK EFFECTS | Unknown |
| Compazine DURATION OF ACTION | 4 hours |
| Compazine AZ DRUG BOX SUPPLY RANGE | Not carried |
| Verapamil GENERIC NAME | Verapamil |
| Verapamil BRAND NAME | Isoptin |
| Verapamil CLASS | Antiarrhythmic |
| Verapamil MECHANISM OF ACTION | Calcium channel blocker. Prolongs av nodal refractory period, dilates coronary arteries, and arterioles. |
| Verapamil INDICATIONS | PSVT, PAT, A-fib and A-flutter with RVR |
| Verapamil CONTRAINDICATIONS | 2nd or 3rd degree AV block, S.S.S., hypotension, CHF, pulmonary edema, wide complex tachycardia, <12 months of age. |
| Verapamil ADVERSE REACTIONS | Hypotension, AV block, Bradycardia, Asystole, dizziness, HA, N/V, peripheral edema. |
| Verapamil INCOMPATABILITIES/DRUG INTERACTIONS | Increases serum concentration of digoxin. Antihypertensives may potentiate Hypotensive effects. |
| Verapamil DOSE/ROUTE Adult | 2.5-5mg IV bolus over 2 minutes. Repeat doses of 5-10mg may be given every 15-30 minutes to a maximum of 20mg. |
| Verapamil DOSE/ROUTE Pediatric | 0.1-0.2 mg/kg/dose IV, IO push over 2 minutes. Repeat dose in 30 minutes if not effective. Don’t use in children <12 months |
| Verapamil ONSET OF ACTION | 5 minutes |
| Verapamil PEAK EFFECTS | Variable |
| Verapamil DURATION OF ACTION | 60 minutes |
| Verapamil AZ DRUG BOX SUPPLY RANGE | 10mg |
| Nitrous Oxide GENERIC NAME | Nitrous Oxide |
| Nitrous Oxide BRAND NAME | Nitronox |
| Nitrous Oxide CLASS | Gaseous analgesic and anesthetic |
| Nitrous Oxide MECHANISM OF ACTION | Affects cns phospholipids |
| Nitrous Oxide INDICATIONS | pain, anxiety, apprehension |
| Nitrous Oxide CONTRAINDICATIONS | Decreased LOC, head injury, undiagnosed abdominal pain or marked distention, hypotension, COPD, cyanosis. |
| Nitrous Oxide ADVERSE REACTIONS | Dizziness, drowsiness, apnea, cyanosis, N/V, malignant hypothermia, euphoria. |
| Nitrous Oxide NOTES ON ADMINISTRATION | NOS increases the incidence of spontaneous abortion. |
| Nitrous Oxide INCOMPATABILITIES/DRUG INTERACTIONS | NONE |
| Nitrous Oxide DOSE/ROUTE dult and pediatric | pt will inhale deeply through mask or mouth piece. |
| Nitrous Oxide ONSET OF ACTION | 5 minutes |
| Nitrous Oxide PEAK EFFECTS | Variable |
| Nitrous Oxide DURATION OF ACTION | 5 minutes |
| Nitrous Oxide AZ DRUG BOX SUPPLY RANGE | 50/50 mix nos and oxygen. (optional) |
| Atrovent GENERIC NAME | IPRATROPIUM BROMIDE |
| Atrovent BRAND NAME | Atrovent |
| Atrovent CLASS | anticholinergic, bronchodilator |
| Atrovent MECHANISM OF ACTION | Anticholinergic (Parasympatholytic) agent appears to inhibit vagally-mediated reflexes by antagonizing the action of acetylcholine. |
| Atrovent INDICATIONS | bronchospasm assoc. with COPD. To be used either alone or in combination with albuterol. |
| Atrovent CONTRAINDICATIONS | hypersensitivity to Atrovent or to atropine and its derivatives. used with caution in narrow angle glaucoma. |
| Atrovent ADVERSE REACTIONS | Coughing, Dizziness, Tremor, Nervousness, Nausea |
| Atrovent NOTES ON ADMINISTRATION | None |
| Atrovent INCOMPATABILITIES/DRUG INTERACTIONS | None. |
| Atrovent DOSE/ROUTE | 500 mcg in 2.5 ml NS via SVN |
| Atrovent ONSET OF ACTION | 15 minutes |
| Atrovent PEAK EFFECTS | 2hours |
| Atrovent DURATION OF ACTION | 8hours |
| Atrovent AZ DRUG BOX SUPPLY RANGE | 5ml. |
| Narcan GENERIC NAME | Naloxone Hydrochloride |
| Narcan BRAND NAME | Narcan |
| Narcan CLASS | Narcotic antagonist |
| Narcan MECHANISM OF ACTION | Competitive inhibition at narcotic receptor sites. |
| Narcan INDICATIONS | Narcotic overdoses |
| Narcan CONTRAINDICATIONS | Use with caution in narcotic dependent patients. |
| Narcan ADVERSE REACTIONS | Withdrawal symptoms, N/V, diaphoresis, tachycardia, hypertension. |
| Narcan INCOMPATABILITIES/DRUG INTERACTIONS | Incompatible with bisulfite and alkaline solutions. |
| Narcan DOSE/ROUTE Adult: | 2.0 mg IV, IM, SC, or ET. Repeat every 5 minutes to a max of 10mg. |
| Narcan DOSE/ROUTE Peds | 0.1 mg/kg/dose IV, IM, SC, ET. Max dose of 0.8mg. May repeat once in ten minutes if needed. |
| Narcan ONSET OF ACTION | 2minutes |
| Narcan PEAK EFFECTS | Variable |
| Narcan DURATION OF ACTION | 60 minutes |
| Narcan AZ DRUG BOX SUPPLY RANGE | 10mg |
Created by:
klindley