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Antidiarrheals
3312 Test #3
| Question | Answer |
|---|---|
| What are the most effective nonspecific antidiarrheal drugs? | Opiates and Opiate Derivatives |
| Name two opiate/opiate derivative antidiarrheals | Loperamide (imodium) and diphenoxylate with atropine (Lomotil) |
| Would you give antidiarrheal drugs with:Antibiotic associated colitis | No |
| Would you give antidiarrheal drugs with:Relatively severe diarrhea in young children and older adults | Yes |
| Would you give antidiarrheal drugs with:HIV/AIDs associated diarrhea | No |
| Would you give antidiarrheal drugs with:Diarrhea caused by toxic materials | No |
| Would you give antidiarrheal drugs with: Microorganisms that penetrate the intestinal mucosa | No |
| Would you give antidiarrheal drugs with:Chronic inflammatory bowel disease | Yes |
| Would you give antidiarrheal drugs with:severe or prolonged diarrhea for more than 2 days | Yes |
| What is the main adverse effect of antidiarrheal medications | Constipation |
| What type of patient would Alosetron (Lotronex) be used for? | A woman with severe diarrhea-predominant irritable bowel syndrome |
| What are the potential serious adverse effects of Alosetron (Lotronex)? | GI obstruction, perforation, hemorrhage, ischemic colitis. |