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Oral Solutions 3
Oral Solution 3 - DDS II
| Question | Answer |
|---|---|
| True or False: External D&C dyes are restricted for use in externally applied drugs and cosmetics. | True |
| True or False: For liquid products usually 0.001% to 0.0001% is enough to impart satisfactory color. | True |
| True or False: For liquid products usually 0.01% to 0.001% is enough to impart satisfactory color. | False |
| True or False: For liquid products usually 0.1% to 0.01% is enough to impart satisfactory color. | False |
| True or False: Common household utensils can be used to measure oral medications. | False |
| True or False: Common household utensils should not be used to measure oral medications. | True |
| What is the best method of giving a liquid medication to an infant or small child? | Oral syringe or calibrated dropper |
| Bitter taste is associated with what type of compounds? | One of the ions in a salt is a high-molecular weight compound, free bases and amides, or nitrogenous compounds |
| Sour taste is associated with what type of compounds? | H+ ions |
| Salty taste is associated with what type of compounds? | Inorganic or low-molecular weigh ionic compounds |
| What is added to an oral solution to improve palatability of a bland preparation? | Flavors and sweeteners2 |
| Polyhydroxy compounds, saccharin compounds and aspartame are all ___________. | Sweeteners |
| Which sweetener is not stable to heat? | Aspartame |
| True or False: Colors can be added to drug products to disguise poor product quality. | False |
| Aspartame is used in oral solution as a _________. | Sweetener |
| In oral solution, methyl-, propyl-, and butylparabens are used as ___________. | Preservatives |
| True or False: Acidic drugs usually taste sour. | True |
| True or False: Inorganic low molecular ionic compounds usually taste salty. | True |
| True or False: High molecular weight drugs usually taste bitter. | True |
| Sorbic acid is what kind of preservative? | Antifungal preservative |
| Benzyl alcohol is what kind of preservative? | Antimicrobial preservative |
| True or False: Inorganic low molecular ionic compounds are usually tasteless. | False |
| True or False: FD&C dyes may be used in foods, drugs, and cosmetics. | True |
| What is the USP? | The USP lists the solubility of drugs and the number of mL in which 1 gram of solute is dissolved. |
| When too much water is added to a spirit, what can happen. | Aromatic substance will salt out. |
| True or False: When diluting a medicated elixir with a non medicated elixir, the alcohol concentration is not important as long as it can be calculated at the end. | False |
| True or False: When diluting a medicated elixir with a non medicated elixir, the diluent should have the approximate alcohol concentration as the elixir being diluted. | True |
| Define spirit. | Alcoholic or hydro-alcoholic solutions of volatile or aromatic substances (alcohol >60%) |
| Define glycogenetic. | Converted into glucose in the body |
| To avoid heat-induced inversion of sucrose, what method may be used to prepare a syrup? | Agitation |
| How are tinctures stored? | In tightly closed bottles and protect from heat |
| True or False: A spirit is an alcoholic or hydro-alcoholic of volatile or aromatic substances. | True |
| What are four desirable properties of sweeteners? | Colorless/odorless/soluble in water; pleasant taste with not bitter after-taste, Chemically stable of broad pH range and temperature; Noncarcinogenic and nontoxic |
| The three polyhydroxy compounds are: | Sucrose, Sorbitol, and Mannitol |
| The two Saccharin comounds are: | Saccharin and Saccharin sodium |
| The following are all considered what type of preservative: Methyl-, propyl-, and butyl-paraben; benzoic acid; sorbic acid; sodium benzoate; and sodium propionate? | Antifungal preservative |
| True or False: Polyhydroxy compounds are usually sweet. | True |
| True or False: High molecular weight compounds are usually tasteless. | False |
| Sodium benzoate is what kind of preservative? | Antifungal preservative |
| True or False: D&C dyes may be used in foods, drugs, and cosmetics. | False |
| True or False: External D&C dyes are restricted for use in externally applied foods, drugs and cosmetics. | False |
| What is used to increase the palatability of oral liquid, to achieve desirable mouth feel, and to improve perceived flavor of oral liquids by reducing bad tasting drugs with the taste buds on the tongue? | Viscosity inducing agents |
| What aqueous solution does not support microbial growth? | Aqueous acids |
| What four methods are used to imrove the palatability of a drug in an oral solution? | Physical, Chemical, Physiological, and Refrigeration |
| True or False: Refrigeration will improve the palatability of an oral solution. | True |
| True or False: Refrigeration does nothing to improve the palatability of an oral solution but is often necessary to prevent microbial growth. | False |
| What is the most popular sugar in syrups? | Sucrose |
| What is the second most popular sugar in syrups? | Dextrose |
| True or False: If Simple Syrup is diluted preservatives are needed since sucrose will no longer prevent microbial growth. | True |
| Sodium propionate is what kind of preservative? | Antifungal preservative |
| True or False: A tincture is an alcoholic or hydro-alcoholic from vegetable substances or non-volatile substances. | True |
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