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Oral Solutions 2

Oral Solution 2 - DDS II

QuestionAnswer
True or False: Propylene glycol has properties that make it useful as a preservative. True
True or False: Propylene glycol has properties that make it useful as a colorant. False
True or False: Glycerin has properties that make it useful as a colorant. False
Why are antioxidants used in an oral solution? To prevent degradation due to oxidation.
Propylene glycol is what kind of preservative? Antimicrobial preservative
True or False: Glycerin has properties that make it useful as a preservative. True
True or False: Glycerin has properties that make it useful as a sweetener. True
Why are perfumes used in an oral solution? To give it a particular smell
Why are buffers used in an oral solution? To maintain pH to protect the drug from pH related instability
Alpha tocopherol, ascorbic acid, butylhydroxytoluene, sodium ascorbate, and socium bisulfite are all examples of _____________. Antioxidants used in oral solutions
True or False: A sour drug tastes best when flavored with salty, or sweet flavors. False
True or False: A bad tasting drug can be rendered tasteless by using less soluble form of the drug. True
True or False: Emulsifying oils does nothing to improve the palatability of an oil. False
True or False: Oils can be emulsified to improve palatability. True
True or False: A viscous vehicle will not reduce the contact of the drug with the taste buds on the tongue and therefore does not improve the palatability. False
True or False: A viscous vehicle can be used to reduce the contact of the drug with the taste buds on the tongue. True
What is the advantage and disadvantage of preparing a syrup by agitation? Maximum stability; More time-consuming
How can a syrup be preserved without adding preservatives? Storage at low temperature; High concentration of sucrose as a part of the formulation
What is an elixir? A sweetened, hydro-alcoholic solution intended for oral use
True or False: The proportion of alcohol present in elixirs varies from 4-40%. True
True or False: The proportion of alcohol present in elixirs varies from 3-30%. False
What is the preservative used in elixirs? Alcohol
True or False: A tincture is an alcoholic or hydro-alcoholic of volatile or aromatic substances. False
What is missing from the dry powder for solution? Solvent
True or False: Acidic drugs are usually tasteless. False
True or False: The proportion of alcohol present in elixirs varies from 5-50%. False
True or False: For solid products usually a 0.1% is enough to impart uniform pastel color. True
True or False: For solid products usually a 0.01% is enough to impart uniform pastel color. False
True or False: Inorganic low molecular ionic compounds usually taste sweet. False
Benzoic acid is what kind of preservative? Antifungal preservative
Methyl-, propyl- and butyl-parabens are what kind of preservatives? Antifungal preservatives
Benzalkonium chloride is what kind of preservative? Antimicrobial preservative
What two ways are there of improving the palatability of an oral solution? Add an anesthetizing agent; Take with a carbonated beverage (CO2 anesthetizes the taste buds)
What are the three main categories or oral solutions? Syrups, elixir, and dry mixture for solution.
A concentrated, aqueous preparations of a sugar or sugar-substitute with or without added flavoring agents and medicinal substances are called ______. Syrups
A syrup containing flavoring agents but not medicinal substances are called ________. Nonmedicated or flavored vehicles (syrups)
True or False: The sucrose in Simple Syrup can prevent microbial growth. True
True or False: Dry mixture for solution is considered an oral solution. True
True or False: If Simple Syrup is diluted there is no need for preservatives since sucrose will prevent microbial growth. False
What are the componenets of a sucrose, or non-sucrose based syrup? Sugar, antimicrobial preservative, flavorant and colorant
What components are good for syrups for diabetic patients? Methylcellulose and hydroxythylcellulose
When adding and alcohol soluble substance and a water soluble substance together, which is added to which? Water soluble substances are added to alcohol soluble substances.
True or False: Syrups are better than elixirs from maintaining both water-soluble and alcohol-soluble components in solution. False
True or False: Elixirs are better than syrups from maintaining both water-soluble and alcohol-soluble components in solution. True
Define tincture. Alcoholic or hydro-alcoholic solutions from vegetable substances or non-volatile substances.
True or False: Oral rehydration solutions (for diarrhea) can be mixed with milk or fruit juices for rehydration. False
True or False: Oral rehydration solutions (for diarrhea) should not be mixed with or given with other electrolyte-containing liquids, such as milk or fruit juices. True
True or False: A solution is not necessarily completely homogenous. False
Why is the therapeutic response faster with oral solutions? The drug in solution is immediately available for absorption
What are five disadvantages of solutions? Dose inaccuracy, Unpleasant taste, Bulky, Instability, Microbial contamination
True or False: The taste of a drug is usually more pronounced in a solid form than in a solution. False
True or False: The taste of a drug is usually more pronounced in a solution than in a solid form. True
True or False: Solutions are stable and therefore do not require the incorporation of a preservative. False
How should patients with difficulty swallowing solids take a medication? Place the dose on the back of the tongue and tilt the head forward.
What is added to an oral solution to mask an unpleasant taste of an active ingredient? Flavors and sweeteners
Created by: P1StudyStack
 

 



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