| Question |
Answer |
| Week 1 |
BLASTOCYST implantation |
| Week 2 |
Bilaminar disk (epiblast & hypoblast) |
| Week 3 |
Gastrulation, primitive streak + notochord + Neural Plate |
| Week 3-8 |
Neural tube, Organogenesis, Teratogen susceptibility |
| Week 4 |
Heart beat, limb buds form |
| Week 10 |
Genital differentiation |
| Alar plate |
Sensory |
| Basal plate |
motor |
| Adenohypophysis origin |
Surface ectoderm |
| Neuroectoderm Derivatives |
CNS |
| Neural Crest Derivatives |
ANS, melanocytes, chromaffin & enterochromaffin, Pia & arachnoid, parafollicular C cells, laryngeal cartilage, skull |
| Endoderm Derivatives |
Gut tube & projecting organs + Thymus, Parathyroid, Thyroid |
| Mesoderm Derivatives |
Dura matter, CT, bone, muscle, heart, lymph, blood, urogenital & kidneys, serous lining, spleen, adrenal cortex |
| Mesodermal defects |
VACTERL: Vertebral, Anal atresia, cardiac, T-E Fistula, Renal, Limb (bone, muscle) |
| Fetal Alcohol Syndrome |
Inhibition of cell migration -> development retardation, microcephaly, facial abnormalities, limb dislocation, heart & lung fistulas |
| ACE inhibitors |
Renal damage |
| Cocaine |
Development abnormalities & addiction |
| Iodide |
Goiter, hypothyroid |
| Vitamin A |
Birth defects |
| Thalidomide |
Limb defects “flipper” |
| Tobacco |
Preterm, placental probs, ADHD |
| Warfarin, x-rays, anticonvulsants |
Multiple anomalies |
| Right cardinal vein |
SVC |
| Left horn of Sinus Venosus |
Coronary Sinus |
| Hemoglobin A |
Spleen from wk 9-28, bone marrow afterwards |
| Hemoglobin F |
Liver, week 6-30 |
| Ligamentum teres hepatis (in falciform lig) |
Umbilical vein |
| Branchial/Pharyngeal Arch 1 |
Mandible + Muscles of mastication, inferior jaw (Mylohyoid & ant belly of digastric. Inner Ear: Malleus, incus + tensor tympani/veli palatini. Anterior tongue. CN V2, 3 |
| Branchial/Pharyngeal Arch 2 |
STAPES, styloid, anterior hyoid, stylohyoid ligament & muscle, posterior digastric, Facial expression muscles. CN 7 |
| Branchial/Pharyngeal Arch 3 |
Greater Hyoid, stylopharyngeus. CN 9, posterior tongue (w/#4) |
| Branchial/Pharyngeal Arch 4 |
Pharyngeal constrictors, levator veli palatini, posterior tongue (w/#3). Superior laryngeal CN 10. w/6: Cartilage of the throat: corniculate, cuneiform, arytenoids, cricoid, thyroid. |
| Branchial/Pharyngeal arch 6 |
Intrinsic laryngeal muscles (minus cricothyroid). Recurrent laryngeal CN 10. w/4: Cartilage of the throat: corniculate, cuneiform, arytenoids, cricoid, thyroid. |
| 1st Branchial/Pharyngeal cleft & pouch |
1st Cleft: External auditory meatus. 1st Pouch: Middle ear, eustachian tube |
| 2nd Branchial/Pharyngeal Pouch |
Palatine tonsils |
| 3rd Branchial/Pharyngeal Pouch |
Dorsal: Inferior Parathyroid. Ventral: Thymus |
| 4th Branchial/Pharyngeal Pouch |
Superior parathyroid |
| Tongue Innervation |
Ant 2/3- Taste CN 7, Sensory CN V3. Posterior 1/3: Taste & sensation CN9,10. Motor CN 12 |
| Urogenital Sinus Derivatives |
Male: Corpus spongiosum, bulbourethral/Cowper’s glands, prostate glands. Female: Vestibular bulbs, Bartholin glands, Urethral & paraurethral glands (of skene) |
| Urogenital Fold Derivatives |
M: Ventral shaft of penis. F: Labia Minora |
| Genital Tubercle |
Glans penis, clitoris |