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patho digestive syst

patho

QuestionAnswer
salivary glands produce___linter(s) of saliva per day 1 Liter
increases salivation parasympathetic
decrease amount of saliva sympathetic
controled by the sutonomic nervous system Esophagus
prevents reguritation of stomach contents cardiac sphincter
three parts of the stomach in order fundus, body, antrum
stomach pH 4
motility is increased by gastrin
motility decreased by secretin
protects the stomach from the acids mucus
converted to pepsin in the environment of acidic gastric juices pepsinogen
inactivated by alkaline environment pepsin
produced by G cells in the stomach Gastrin
Gastrin stimulates the secretion of HCL, pepsinogen, intrinsic factor, pancreatic enzyme, insulin
seeing smelling tasting chewing stimulating via the vagus nerve, the secretion of gastri, HCL, and prpsinogen Cephalic phase
food, particularly proteins and distention of the stomach Gastric phase
digested proteins stimulate secretion of acid by stomack intestinal phase
has villi and microvilli for absorption small intestine
duodenum jejunum ileum parts of the small intestine
inflamation of the peritoneum peritonitis
generally suppresses sympathetic
generally sitmulates parasympathetics
increased by chme comming to it from the stomach. Motility
from teh duodenum, decrease GI motility and stimulates pancrease to make an alkaline juice secretin
hormone that is released from the duodenum, stimulates gallbladder to eject bile and pancrease to make enzyme rich fluids cholecystokinin
activates pancreatic enzyme trypsinogen and chymotrypsinogen and is released when chyme is in the stomach enterokinase
major function of the small intestine absorption
absorbs 5-8 liters of water a day duodenum
doesnt absorb much water large intestine
parts of the large intestine cecum colon rectum
intrinsic, controlled by autonomic nervous system internal anal sphincter
voluntary external sphincter
causes fecal particles to adhere to each other mucus
stimuli of defecation distention of rectal wall starts the reflex that relaxes the internal sphincter and intensifies peristalsis
most disorders of the digestive system are chronic
___GI problems can be serous due to F&E problems Acute
most common frequent digestive complaint in the US constipation
increased in defecation frequency or in teh fluidity and volume of feces diarrhea
three types of pain parietal,visceral, referred
localized and intense pain parietal
poorly localized and dull pain visceral
pain felt at some distance from the affected organ referred
causes of upper GI bleeds ulcers, bleeding varices in the esophagus
causes of lower GI bleeds hemorrhoids, crohn's, cancer, inflammatory diseases
test for blood in the GI tract hemacult test
acute large losses of blood lead to shock
difficulty swallowing dysphagia
difficult swallowing due to nerual problems that results in loss of neuromuscular coordination in teh lower esophagus. Leads to obsturction and distention of the esophagus Achalasia
reflux of acidic chyme from teh stomach to the esophagus GERD
herniation of a portion of the stomach into chest through a hiatus in the diaphram Hiatal hernia
90% of herniations, gastroesophegeal junction slides up higer than it shoul be Sliding
LES does not roll up into chest, just part of teh fundus of the stomach. can impede blood flow to the stomach and lead to gastritis and ulcers rolling
inflammatory disoder that erodes the stomach surface epithelium in a diffuse of localized pattern acute gastritis
associated with chronic inflammatory changes and thinning and degeneration of teh muscle wall of the stomach can result in pernicious anemia or decrease in HCL production chronic gastritis
a break in the mucosal lining of the lower esophagus, stomach or small intestine peptic ulcer disease
risk factors for peptic ulcer disease H. Pylori, alcohol, NSAIDS, caffeine, Bile reflux
most frequent occuring, males more than females, occurs in ages 20-50 most commonly, H.Pylori present duodenal ulcer
chronic epigastric pain that begins 2-3 hours after eating when the stomach is empty and in the middle of the night, pain relieved by food, see more in the spring and fall clinical manifestations of duodenal ulcers
less frequent occur after age 50 associated with cancer, usually in lower part of stomach down stream from acid and pepsin gastric ulcer
pain relieved or increzased by food, blood in vomit and stool characteristics of gastric ulcers
burn injury related curling(ischemic) ulcer
CNS related associated with sever head trauma or brain surgery cushing ulcer
may be slow bleeding may show as blood in the stool, shock, ineffective perfusion of organs, hypotension, hypoxemia and hypoxia major complications of peptic ulcer disease
due to rapid entry of hypertonic stomach contents into the duodenum dumping syndrome
malabsorption of iron Anemia
obstructions that are mechanical intrinsic lesions, extrinsic
obstruction that is functional paralytic ileus
infants have hypertrophied sphincter muscle which doesnt let food pass from the stomach pyloric stenosis
obstruction in infant caused by the telescoping of one part of teh colon on another part intusssusception
congenital aganglionic megacolon Hirschsprung's disease
twisting of teh intestines on its mesenteric pedicle volvulus
decreased bowel sounds after surgery paralytic ileus
the higher the obstruction the quicker you will see vomiting
may comprimise resp. function distention
the lower the obstruction the more the distention
classification is done by using the Dukes stages A-D cancer of the bowel
anywhere in the GI tract, seen in ages 10-30, autoimmune disease, transmural, 80% of small intestine involved, has skip lesions, non bloody diarrhea, low malignancy, right sided pain, 50% rectal involvment Crohn's Disease
goes through the mucosa and submucosa, small intestine involvment normal, continuous lesions, bloody diarrhea, higher malignancy after 10 years, pain on left side more common and 95% of rectum involvment ulcerative colitis
inflammation of vermiform appendix more likely to affect youth ages 10-19 appendicitis
congenital absence of normal opening i the esophagus esophageal atresia
anus never developed so there is no way to get fecal matter through imperforated anus
Created by: dnoyes
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