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Clinical Tests

Define clinical tests purpose

ACRONYMWhat is it?Organ or tissue of originHow it is eliminated or metaboPhysiological meaningIn relation to disease
BUN Blood Urea Nitrogen By product of protein metabolism results from the detoxification of Ammonia All tissues which break down protein or amino acids-detoxification of ammonia occurs by means of a liver enzyme passively filtered by the kidney. Produced in higher concentrations than Creatinine, therefore changes in levels occur sooner than creatinine - hence use of BUN/Creatinine ratio High-excess protein degradation Inefficient filtering Hemoconcentration low - not enough protein intake(muscle mass however can substitute for source of protein) more commonly liver disease causing loss of enzyme that makes it. Too effnt filtg Dil High:Atkins diet,Kidney disease that impacts filtration rate,Dehydration,GI bleeding,Heart failure,Shock. Liver failure,pregnancy,Any event with increased renal filtration overhydration
CREAT(Creatinine) (blank) (blank) (blank) (blank) (blank)
Glucose (sugar) (blank) (blank) (blank) (blank) (blank)
AST (blank) (blank) (blank) (blank) (blank)
ALT (blank) (blank) (blank) (blank) (blank)
CK (CPK) (blank) (blank) (blank) (blank) (blank)
Myoglobin (blank) (blank) (blank) (blank) (blank)
Troponins Part of the structure of muscle fibers in heart and other muscle Muscle/heart Comes in several flavors I, T degraded by proteases High- Tissue damage resulting in loss of membrane integrity-early event in diagnosisng MI Muscle Damage Crush injuries MI-
CBC Complete Blood Cell Count, includes a whole lot of measurements which will be discussed later Bone marrow in response to environmental ( internal environment) conditions Reticuloendothelial system ( macrophages and spleen) See individual components (i.e WBC) (blank)intentionally
WBC WBC (blank) (blank) (blank) (blank)
RBC RBC (blank) (blank) (blank) (blank)
HGB HGB respiratory pigment in red cells, iron, porphyrin ring and globin chains- made in red cells Reticuloendothelial system - hemoglobin is processed to bilirubin which is conjugated ( made soluble by the liver)-excreted as bile and bilerubin derivatives (blank)intentionally (blank)intentionally
HCT HCT also known as PCV - cellular mass in blood described as a percentage reflects most closely the number and mass of RBCs so see RBC for meaning intentionally blank intentionally blank
Platelets Platelets Cells responsible for orchestrating coagulation, inflammation and tissue repair- short-lived Reticuloendothelial system - dismantled by Macs, used up in routine mainetenance and repair intentionally blank intentionally blank
DIFF DIFF intentionally blank intentionally blank Balance of different cells, reflect both production and destruction of each subtype of white cell independently intentionally blank
Protime Laboratory measure of the functional integrity of the Extrinsic coagulation system Liver degraded by plasma proteases Marked decrease or functional loss of integrity of any or all of the following VII X, II, I hereditary or acquired coagulation cascade defects
PTT Laboratory measure of the functional integrity of the Intrinsic Coagulation system Liver degraded by plasma proteases Marked decrease or functional loss of integrity of any or all of the following PreKallekrein, High Molecular Weigth Kininogen, XII, XI, IX,VIII, X, II,I hereditary or acquired coagulation defects
Blood Gases PH Oxygen CO2 intentionally blank Controlled by Lungs and Kidney Metabolic and Respiratory Events by means of plasma, red cell and protein buffer systems, active transport across the renal tubular structures and ventilatory rate. Alterations in blood flow, composition, Renal function and respirator function as well as environmental conditions. TNTL
Created by: silvlaur
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