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Penicillins ch12
Mosby's Chapter 12 Antiinfective
Question | Answer |
---|---|
Who is at the highest risk of infections? | Infants, young children, and elderly people, people with poor circulation, poor nutrition, or multiple diseases, immunocompramised. |
What organism causes infection | Pathogen |
What are antimicrobials | Chemicals that kill or damage pathogenic organisms |
Bacteriostatic | Limit or slow the growth of the bacteria, weakening or eventually leading to the death of the bacteria. |
Bactericidal | Kill the bacteria |
Spectrum | The number of organisms the medication is effective against |
Narrow-spectrum drugs | (Sharp shooter) effective against only a few organisms |
Broad-spectrum drugs | (Shotgun) effective against a wide variety of organisms |
Superinfection | When organisms that are not sensitive to a prescribed antibiotic overgrow and get out of control (cause yeast infections) |
What is Penicillins Action? | Interferes with creation of the mucopeptide cell wall |
What spectrum is Penicillin | Penicillins are broad spectrum and kill both gram positive and gram negative organisms |
What microbes are penicillins effective in treating | Rat bite fever, gonnorrhoae, syphilis, Neisseria meningitidis, Staphylococcus. |
Penicillin Prophylactic treatment for | Bacterial endocarditis, CHD, some dental procedures, surgers of upper resp tract, GI tract |
Adverse Reactions to Penicillin include: | Neuropathy (nerve damage) uticaria, nausea, vomiting, anemia, rash, erythema, angioedema, laryngeal edema, anaphylaxis |
Is penicillin bacteriostatic or bacteriocidal | Bacteriocidal. |
Drug Interactions with Penicillin | Tetracycline, erythromycin, Probenecid, oral contraceptives, Antacids |
What may prolonged use of Penicillin cause | Liver, kidney or blood disorders |
How many days should penicillin be given for | 10 days (at least) |
What route can penicillin go | PO, IM (NOT IV!) |
Other food contraindications of Penicillins | acidic juices, coffee and soda |
Types of Natural Penicillins | Penicillin G Penicillin V |
What is the trade names of Penicillin G | Bicillin Permapen Pfizerpen Wycillin Bicillin CR |
What are the penicillinase resistant penicillins | Cloxacillin Dicloxacillin Nafcillin Oxacillin |
What are the Aminopenicillins: Broad spectrum Penicillins | Amoxicillin Amoxicillin and clavulanate Ampicillin Ampicillin sodium Ampicillin sodium and sulbactam sodium bacampicillin |
What are the trade names of amoxicillin | Amoxil Moxilin Sumox Trimox |
What is the trade name of amoxicillin and clavulanate potassium | Augmentin |
What is the trade name of ampicillin | Principen |
What is the trade name of ampicillin sodium and sulbactam sodium | Unasyn |
What are the Extended spectrum penicillins | Piperacillin Piperacillin sodium and tazobactam sodium tiacarcillin Ticarcilland and clavulanate sodium |
What is the trade name of piperacillin sodium and tazobactam sodium | Zosyn |
What is the trade name of ticarcillin | Ticar |
What is the trade name for ticarcillin and clavulanate sodium | Timentin |
What should you do before administering IM pen? | Take patient's BP and pulse |
How long before a person receiving IM Pen can leave? | 30 minutes |