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chpt 49 study guide
Diabetes
Question | Answer |
---|---|
in addtion to promoting the transport of glucose from the blood into the cell. insulin also does what? | accelerates the transport of amino acids into cells & their synthesis into protein |
tissues that require insulin for the glucose transport are (2) | skeletal muscle, and adipose |
during the development of type 1 DM, the B-cell response to hyperglycemia can be identified in the blood and urine by the presence o | pro-insulin B-peptides |
2 hormones released during physical and emotional stress & are counter-regulatory to insulin are | cortisol and epinephrine |
the type of diabetes strongly related to HLA- human leukocyte antigen | type 1 |
insulin resistance | type 2 |
B-cell secretory exhaustion | type 2 |
inherited defect in insulin RECEPTORS | type 2 |
production of islet-cell antibodies | type 1 |
genetic susceptibility for antibody production | type 1 |
inappropriate glucose production by the liver | type 2 |
B-cell destruction | type 1 |
impaired glucose tolerance which occurs gradually | type 2 |
compensatory-increased insulin production | type 2 |
describe polyuria | high glucose levels caused by loss of glucose in urine w/osmotic diuresis |
describe polydipsia | thirst caused by fluid loss of polyuria |
describe polyphasia | CELLULAR STARVATION FROM LACK OF GLUCOSE & USE OF FAT AND PROTEIN FOR ENERGY |
when teaching a pt with metabolic syndrome, the nurse gives highest priority to teaching on... | maintaining a normal weight |
A pt is admitted to the hospital w/a FBS of 512 mg/dl and arterial PH of 7.38 indicating... | he has enough endogenous insulin to prevent ketoacidosis w/the hyperglycemia |
during a health screening, the pt has a fasting plasma glucose FPG of 132 mg/dl. At a follow up visit, the diagnosis of diabetes is made based on...(select all that apply) | A FPG of > 126 mg/dl or a random plasma glucose of 210 md/dl |
the nurse determines that the pt w/a 2 hr OGGT of 152 has... | impaired glucose tolerance |
when teaching a pt who take 2 units of 70/30 NPH in the morning and at 6 pm, the nurse teaches | importance of set meal pattern w/ a bedtime snack to prevent hypoglycemia |
when teaching a pt about insulin administration | consistently using the same size of the appropriate strength of insulin syringe to avoid dosing errors |
when Lispro insulin (humalog) for a type 1 diabetes pt, the nurse knows it should be administered... | @ mealtime or within 15 min of the meal |
A diabetic pt is learning to mix NPH and regular insulin together. More teaching is needed when he... | draws up the NPH first (to avoid contaminating the regular w/NPH) |
the home care nurse should intervene to correct a pt whose insulin administration includes... | mixing an evening dose of regular with insulin glargine (Lantus)in one syringe for administration |
which agent decreases endogenous glucose production? | TZD |
which agent should be taken w/in 30 min of each meal, & causes rapid and short-acting release of insulin from the pancreas? | meglitinide |
which agent decreases glycogenolysis, is frequently the drug of choice (not), stimulates production of insulin and enhances cellular sensitivity to insulin | sulfonureas |
which agent delays glucose absorption from the GI tract, is not effective w/fasting hyperglycemia, and is take with the first bite of each meal? | alpha glucosidase inhibitors |
which agent increases glucose uptake in the muscles, and has a primary effect of decreasing glucose production by the liver? | biguanide |
in nutritional management of diabetes, it is important for the pt to... | eat regular meals at regular times |
oal of nutritional therapy for the pt w/type 2 diabetes includes... | normal serum glucose and lipid levels |
to prevent hyper/hypoglycemia with exercise, the nurse teaches what about exercise? | that it should be done about 1 hour after eating, when serum glucose levels are rising |
An error in performance of SMBG (self monitoring of blood glucose) may be... | cleaning the puncture site with alcohol before the puncture (oops)- interferes w/test result and dries out fingers |
Recommendation in an outpt screening clinic for diabetes includes... | fasting plasma glucose for all individuals at age 45, then Q3 years |
A pt calls in to report feeling flu-like symptoms & nausea, the nurse advises... | to take usual dose of insulin |
ketoacidosis occurs as a complication when... | the body utilizes large amounts of fatty acids, rather than the glucose for energy |
explain the process of K+ imbalance in ketoacidosis (8 steps) | inc. H+ present(acidic ketones & acetone); K+ from cells moves to blood in exchange for H+; inc serum K+; K+ excreted in urine w/osmotic diuresis; tx w/insulin inc glucose metabolism & dec fat metabolism; dec H+; K+ back into cells; totsl body K+ deficit |
5 SYMPTOMS OF DKA NOT PRESENT IN HYPERGLYCEMIC HYPEROSMOLAR SYNDROME | 1) Kussmal's respirations 2)ketonuria 3)sweet fruity odor to breath 4)decreased arterial ph [acidosis] 5)ketonemia |
difference in tx between DKA and HHS | HHS requires more fluid replacement to correct dehydration |
the nurse is alerted of possible hypovolemic shock by the presence of... | a change from polyuria to oliguria |
hypoglygemia s/s includes... | slurred speech, too much exercise w/out food, and cold/clammy skin |
hyperglycemia s/s include... | n/v, increased dietary intake, precipitated by stress |
s/s of both hyper/hypoglycemia include... | HA, changes in vision |
A call is made about a diabetic pt is found unconscious at home, with no glucometer. The nurse advises | administering glucagon 1 mg IM or SQ |
with diabetes, atherosclerosis dz affecting the major systems occurs... | with a higher frequency and earlier onset than the pt w/out DM |
more teaching on foot care is needed with the diabetic pt who says... | I know I'll have sores on my feet b/c they'll be painful |
A 72 year old woman is dx w/diabetes. The nurse knows that... | she does not need as tight glucose control as a younger pt |
autonomic neuropathy characteristics include... | male impotence and delayed gastric emptying |
microangioplathy characteristics include... | skin spots, basement membrane thickening of capillaries & arteriole, microaneurysm/destruction of retinal cappilaries & diffuse/nodular glomerulosclerosis |
macroangiopathy characteristics include... | altered lipid metabolism, ulceration/amputation of lower extremities, ischemic heart dz |
sensory neuropathy characteristics include... | atrophy of the small muscles of the hands, pain and paresthesia of the legs |
polydipsia and polyuria d/t diabetes is mainly from what? | the fluid shift d/t osmotic from hyperglycemia |
A pt w/type 2 DM is admitted to the hospital, the nurse realizes this pt... | has enough endogenous insulin to prevent ketosis but is at risk of developing hyperosmolar hyperglycemic nonketotic syndrome |
teaching a pt "survival skills for type 1, the nurse... | teaches self-monitoring of glucose |
which therapy (drug) is not appropriate for the pt w/DM | use of diuretics to tx renal problems |
A pt has a serum glucose level of 825 mg/dl and is unresponsive, the nurse suspects DKA as opposed to hyperosmolar hyperglycemic syndrome based on... | rapid deep respiration (Kussmal's) |