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WVC resp meds
WVC respiratory meds
Question | Answer |
---|---|
Name the major bronchodilators | Albuterol(Proventil/Ventolin)rescue Salmeterol (Serevent)-long acting Ipratropium (Atrovent,Apovent)-anticholinergic theophylline (Elixophylline)methylxanthines |
Purpose of albuterol adrenergics | Rescue inhaler.Short acting. Causes bronchodilation by relaxing smooth muscle by binding beta2 recptors |
Nursing interventions for albuterol | Carry with them always, monitor HR, take at least 5 mins b4 other inhal. correct technique for use |
Long acting beta agonists adrenergics | Salmeterol (Serevent) |
Teaching for long acting beta agonists | shake inhaler well, do not use as a rescue inhaler, correct technique |
drug interactions for Salmeterol (Serevent) | beta blockers can decrease action • MAO inhibitors and tricyclic antidepressants potentiate cardiovascular effects. Use with caffeine-containing herbs ( cola nut , guarana , mate , tea , coffee ) ↑ stimulant effect |
anticholinergic asthma drugs | ipratropium (Atrovent) |
ipratropium's action | bronchodilation by INHB PNS, allowing sympathetic to dominate, releasing norepinephrine that activates beta 2 receptors. |
what is ipratropium used fro | as a rescue inhaler and preventative. In place of short term beta2 agonists (due to HR interactions) |
Methylxanthines drugs | theophylline (Elixophylline) |
What is theophylline (Elixophylline) used for | Long-term control of reversible airway obstruction caused by asthma or COPD |
How does theophylline (Elixophylline) work | Inhibit phosphodiesterase(enzyme), producing increased tissue concentrations of cyclic adenosine monophosphate (cAMP)(stimulant). Increased levels of cAMP result in bronchodilation |
Side effects of theophylline (Elixophylline) | N/V, tackycardia, anxiety, GI BLEEDS, TOXICITY, SEIZURES, ARRHYTHMIAS |
Major drug interactions for theophylline (Elixophylline) | Erythromycin, beta blockers, calcium channel blockers, hormonal contraceptives,fluvoxamine,protease inhibitors , quinidine , some fluoroquinolones , and large doses of allopurinol ↓ metabolism and may lead to toxicity |
Nursing implementations for theophylline (Elixophylline) | IV or PO. take w/food or 1-2 hrs after for more rapid abspt. Monitor HR, s/s of toxicity, cardio or GI probls |
anti-inflammatory drugs | Fluticasone (Flovent) Prednisone (Deltasone) corticosteroids, NSAIDS, Nedocromil (Tilade)-mast cells stablizer |
Fluticasone (Flovent) action | corticosteroid:Disrupts all known production pathways of inflammatory mediators. The main purpose is to prevent an asthma attack caused by inflammation or allergies. |
Fluticasone (Flovent) teaching | Teach patient to use the drug daily, even with no symptoms.Perform good mouth care and to check the mouth daily for lesions or drainage. Teach patient to not use this drug with the onset of asthma symptoms or worsening of wheezing. Proper use/demo |
Prednisone (Deltasone, Predone) action | suppresses inflammation and the normal immune response Suppresses adrenal function at chronic doses of 5 mg/day • Has numerous intense metabolic effects Not recommended unless asthma symptoms cannot be controlled with any other therapy. |
Prednisone (Deltasone, Predone) side effects | depression, euphoria, hypertension, acne, ↓ wound healing, ecchymoses, fragility, hirsutism, petechiae.adrenal suppression,muscle wasting, osteoporosis (cushings appearance) |
When is Prednisone (Deltasone, Predone)used | as last resort, when all else isn't working |
Nedocromil (Tilade) action | Stabilizes the membranes of mast cells and prevents the release of inflammatory mediators. Purpose is to prevent asthma attack triggered by inflammation or allergens. |
LEUKOTRIENE ANTAGONIST | Montelukast (Singular) Antileukotriene Agents |
Montelukast (Singular)action | Blocks the leukotriene receptor, preventing the inflammatory mediator from stimulating inflammation. Purpose is to prevent asthma attack triggered by inflammation or allergens. |
Teaching for montelukast (Singular) | Drug has slow onset of action for asthma prevention and is most effective when taken consistently. This drug is for long-term asthma control and does not replace other drugs, especially corticosteroids and rescue drugs. |
IMMUNOMODULATOR | Omalizumab (Xolair) |
Omalizumab (Xolair) action | Drug is an antibody that binds to the IgE receptors on mast cells and basophils, preventing allergens from triggering the release of inflammatory mediators. Purpose is prevention of allergen-triggered asthma attacks. |
Omalizumab (Xolair)side effects | SQ- injection site reaction, increase rate of cancer, anaphylactic shock |
teaching omalizumab (Xolair) | Do not administer more than 150 mg per injection site. Keep patient at the facility for 30-60 min after injection. Teach patient not to decrease the dose of or stop taking any other asthma drugs unless otherwise instructed by the health care professional. |