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Chemo. Drugs
Question | Answer |
---|---|
Antineoplastics | Used to control growth and to relieve symptoms and improve quality of life. |
Cell Cycle Specific Drugs | Antimetabolites (methotrexate/rheamatrex, mercaptopurine/purinethol)- S phase (interfere with cell growth, deprive cell of substances) and Mitotic inhibitors or plant alkaloids (vincristine/oncovin)- M phase(block mitosis) |
Cell Cycle Non-specific Drugs | Alkylating (eisplatinum/platinol AQ, cyclophosphamide/cytoxan)- prevention of cell division. Antibiotic antitumor drugs (doxorubicin/adriamycin) bind to DNA so that DNA and RNA transctiption is blocked. |
Sex Hormone Inhibitor | tamoxifen/nolvadex: block estrogen receptor sites in tumors that are estrogen dependent |
Action of hormone inhibitors | slows growth of cancer cells by changing hormonal environment that is promoting cancer growth |