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T Metabolic Acidosis

Metabolic Acidosis

QuestionAnswer
What relationship exists between HCO3- and CL-? inverse
What are the two main losses or gains that take the body into a state of metabolic acidosis? loss of bicarbonate or gain of metabolic acids (or a combination )
2 ways to have too much H+ increased production, decreased excretion
Name several ways to have too much metabolic acid (C, D, S, F, H, E, S, S) Co2 poisoning, DKA, starvation, fever, hypoxia, ethanol ingestion, salicylate toxicity, sepsis
What could interfere with the elimination of metabolic acids? Renal Failure
2 ways to have too little bicarb underproduction or increased elimination
Name 5 reasons for a shortage of Bicarb.(purld) renal failure, pancreatitis, liver failure, dehydration, uremina
What effect would vomiting and diarrhea have on bicarbonate? Increased elimination
Four symptoms of Metabolic acidosis from Ms. Fowler’s PPT (DKMC) Disorientation, Kussmaul’s respirations, Muscle twitching, Changes In LOC
What is the cause of metabolic acidosis if the anion gap is greater than 14 mEq/L? Metabolic acids
What type of acid is not considered a metabolic acid? carbonic acid
What will the anion gap measurement look like if the cause of metabolic acidosis is a loss of bicarbonate? normal – between 8 and 14 mEq/L
One way to have too much metabolic acid is the development of Ketones. What are ketones? a metabolic by product of the catabolism of fatty acids when glucose supplies are depleted.
One way to have too much metabolic acid is the development of Ketones. Name 6 conditions that could put a patient in a state of Ketosis. (D, C,S, S, D, H, S, ) Diabetes mellitus, chronic alcoholism, severe malnutrition or starvation, deficient carbohydrate intake, hyperthyroidism, severe infection with fever (hypermetabolic state)
What causes lactic acidosis? Cells receive too little oxygen and are forced to metabolize glucose anaerobically which leads to lactate formation.
What conditions can lead to lactic acidosis? conditions that cause metabolic demands to exceed oxygen supply such as shock, heart failure, pulmonary disease, hepatic disorders, seizures, or strenuous exercise
How would renal dysfunction contribute to metabolic acidosis? decreased ability to excrete acids
What affect does hyperthyroidism have on metabolism? speeds it up
What is the first manifestation of metabolic acidosis? increased depth and rate of breathing/ Kussmaul’s respirations
Patients with what disorder may have fruity breath with kussmaul’s respirations? diabetes – ketones
What are the CNS signs of metabolic acidosis in order of development? lethargy, dull headache, confusion, stupor, coma
What happens to the cardiovascular system with metabolic acidosis? Cardiac output and Bp drop, arrhythmias with hyperkalemia
What are the manifestations of metabolic acidosis on skin? at first warm and dry due to peripheral vasodilation, but as shock develops; the skin becomes cold and clammy
What are the GI signs associated with metabolic acidosis? VAN, Vomiting, Anorexia, Nausea
Uncompensated metabolic acidosis ABGs pH low, PaCO2 normal, Bicarb low
Compensated metabolic acidosis ABGs pH normal, PaCo2 low, Bicarb low
Why would potassium be high with metabolic acidosis? excess H+ moves into cells and potassium moves out to maintain balance.
What lab values should be checked to see if our patient with metabolic acidosis has good liver function? (4) BUN and Creatinine, HCT and HGB,
What might our patient receive by IV if their pH gets really low? bicarbonate
What treatment will our diabetic patient with metabolic acidosis need ? What ion may become imbalanced with this treatment? Fast acting insulin will move potassium into the cells and possible lead to hypokalemia.
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