Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
GI - Trogone
GI
| Question | Answer |
|---|---|
| What are antiulcer drugs? | Antacids, H2 Blockers, PPI (Proton Pump Inhibitors), Pepsin Inhibitor, Prostaglandin Analogue |
| Where does most drug absorption occur? | In the Duodenum |
| What is absorbed in the stomach? | Lipid soluble drugs and alcolhols |
| What do glands secrete? | Mucus, Pepsinogen, Bicarbonate, HCl, Intrinsic factor, Gastrin, Serotonin, Hormonal products |
| Gastrin hormone | Gastrin producing cells |
| HCl acid, Intrinsic factor, Needed for absorption of Vitamin B12 | Parietal Cells |
| Chief Cells break down protein | Pepsinogen - pepsin (enzyme) |
| Mucous producing cells | mucous |
| Histaminestimulates production of HCl | Enterochromaffin-like (ECL) cells |
| Somatostatin (inhibitory) | D-Cells |
| D-cells | at the end of the digestive cycle to reduce acids |
| Gastrin produces what? | Hcl and pepsinogen |
| Vagus nerve is stimulated by what? | sight, taste, smell |
| food in stomach causes what to be released? | Histamin |
| What completes the digestion of fats, carbs, and protein? | hormones, bile, and pancreatic acid (trypsin, chymotrypsin, lipase, and amylase) |
| What causes a peptic ulcer? | H. pylori,Extreme physiological stress (chemp pts), NSAIDS, Zollinger-Elsin Syndrome (ZES), PUD (peptic ulcer disease) |
| Antacids | Neutralize gastric acid by increasing the pH in the GI tract, reducing pepsin activity |
| Antacids | Excreted in feces (some in urine, breast milk) |
| Antacids | Amphojel, Maalox, Mylanta, MOM, Tums |
| Antacids | Used for indigestion, heartburn (r/o GI vs Cardio), GERD, PUD, hyperphosphatemia |
| MOM | Mg Hydroxide, Diarrhea, Excreted in milk and urine |
| Maalox, Mylanta | Al & MgBalanced |
| Amphojel | Al hydroxide, Binds dietary phosphate, Al intoxication, Constipating |
| TUMS | Ca CO4, Binds dietary phosphate, Milk-alkali syndrome, (Ca OD) |
| What is a Ca OD? | urinary problems, confusion, hypercalcium, renal problems |
| Antacids | Decrease absorption of quinolones, iron, isoniazid, phenytoin, and digoxin - administer 2 hours apart |
| Antacids | Causes premature dissolution of enteric-coated tablets - Administer 1 hour apart |
| Antacid Teaching | Assess Electrolyte imbalances, changes in elimination |
| Antacid Teaching | Take 1-3 hours after a meal, shake suspension well, drink water after chewing, give 1 hour apart from enteric coated pills, heart failure, HTN - so check sodium content |
| H2 Blockers | Inhibit gastric acid secretion by inhibiting the action of Histamine at Histamine2 receptors in gastric parietal cells |
| H2 Blockers | Cimetidine (Tagamet); Famotidine (Pepcid - Q12 hours); Ranitidine (Zantac) |
| What are the indications for H2 Blockers? | GERD, UGIB, ZES Syndrome, PUD |
| H2 Blockers are contraindicated when? | W breast feeding (cimetidine tagamet) |
| H2 caution | pregnant, elderly, impaired renal and hepatic function |
| H2 s/e | HA, dizziness, confusion, mild disrrhea, rash |
| H2 Blocker Cimitidine (Tagamet) | crosses placenta barrier and found in breast milk |
| H2 Blocker Cimitidine (Tagamet) | May increase serum levels and toxicity of benzodiazipines, ca cahnnel blockers, tricyclic antidepressants, procainamide, lidocaine, oral anticoagulants, phenytoin, propranolol, quindine, and theophylline |
| H2 blocker given with Carmustine may increase risk of bone marrow toxicity |
Created by:
Jandian32
Popular Nursing sets