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Stack #38907

RRC Maintenance - Chronic Renal Disease

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chronic renal disease state where kidneys are no longer able to function adequatelyto excrete wastes from the body. Irreversible condition that may develop over months to years...kidneys can adapt and maintain fluid balance until function in really bad
cause of chronic renal disease diabetic nephropathy, hypertension-related kidney disease, glomerulonephritis, polycystic kidney disease
acute on chronic renal failure pre-existing renal insufficiency may experience an acute insult that can be pre-renal, intra-renal or post-renal in nature
stage 1 reduced renal reserve (residual functioning 40-75% of normal, mild reduction in GFR, BUN/Cr normal, no symptoms)
stage 2 renal insufficiency (residual functioning 20-40% of normal, moderate reduction in GFR, decreased solute clearance, ability to concentrate urine and hormone secretion; increase in BUN and Cr - mild azotemia and anemia
stage 3 chronic renal failure (further decline)
stage 4 end-stage renal disease ( residual function <15% of normal, severe reduction in GFR, metabolic acidosis, marked increase in BUN, Cr, PO4; marked decrease in Hgb, Hct, Ca...excretory/regulatory function severely impaired, fluid overload with uremia
signs of symptoms of decreased GFR oliguria/anuria, edema, unexplained SOB, unexplained weight gain
uremia occurs when renal function has significantly declined and GFR is low therefore unable to excrete nitrogenous wastes
hyperkalemia may develop when GFR is already reduced due to decreased ability of kidneys to excrete K+
metabolic acidosis unable to excrete H+ (which usually combines with NH3 and HPO4 and is excreted) and does not effectively reabsorb HCO3-
extracellular volume expansion/excess fluid volume results from failure to excrete Na+ and H20 as a result of GFR <10-15ml/min and compensatory mechanism become exhausted; will manifest as peripheral and pulmonary edema and hypertension
anemia develops from decreased renal synthesis of erythropoietin which is a hormone responsible for bone marrow stimulation of RBC production
hyperphosphatemia unable to adequately excrete PO4...may cause itchy skin or painful joints
hypocalcemia can result in renal osteodystrophy as a result of lack of vitamin D necessary for Ca++ absorption in the gut
pericarditis cause by toxic effects of urea inflamming pericardial membrane
encephalopathy CNS irritation/inflammation from toxins
peripheral neuropathy/restless leg syndrome both thought to be result of irritation and other toxins on peripheral nerves
skin manifestations pruritis most common skin complication due to accumulation of toxic pigments (urochromes) in the skin
diagnostic tests creatinine screening test, BUN, serum Na+ and K+ in blood, serum uric acid, urinalysis tests (protein, albumin, RBC, etc), renal ultrasound, CT scan, KUB imaging
risk factors age, hypertension, diabetes mellitus, prior kidney disease, multiple UTIs
Why is an individual with chronic renal disease placed on a low-protein diet? restricting protein may slow down rate of kidney function deterioration, decreases PO4 load, helps control acid levels in blood and can relieve N+V in advance disease
Why is there Na+ restriction regarding the diet of those with CRD? to control BP by restricting Na which will help decrease water retention and can also cause excess thirst which can be problem when on fluid restriction
peritoneal dialysis use peritoneum as dialysis membrane... dialysate instilled into peritoneal cavity via catheter surgically inserted into abdominal wall, Once in abd. movement of solutes and fluid occurs between person's capillary blood and dialysate. drain at set intvl
hemodialysis blood is removed via special vascular access device through an artificial kidney (dialyzer) and then returned to circulation...can be done LT 2-4x/wk for 3-5hr/treatment
Why are chest sound auscultated in those with CRD? to assess for chest congestion/pulmonary edema
why is temperature monitored in those with CRD? fever is an indicator of infection in those who are immunocompromised
phosphate binders to control hyperphosphatemia
vitamin supplementation water-soluble vitamins are lost during dialysis
erythropoietin-stimulating drug to treat anemia
diphenhydramine to treat pruritis
sodium bicarbonate to treat acidosis
vitamin D preparation/calcium supplementation to treat hypocalcemia and prevent renal osteodystrophy
Created by: bella83
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