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Resp. System & Colds

Respiratory System Alterations and Cold Medications

QuestionAnswer
What causes most viral infections? Rhinovirus or Influenza Virus(Flu)
What is used to treat the common cold? Combined use of antihistamines, nasal decongestants, antitussives, and expectorants.
Does treatment cure the common cold? No, treatment of the common cold is symptomatic only not curative.
what do anthistamines do? They act as anthistaminic, anticholinergics and sedatives.
What is the mechanism of action for antihistamines? They block the action of histamine at the H1 receptor sites. It competes with histamine for binding at unoccupied receptors. It cannot push histamine off the receptor if already bound.
What are the effects of histamine vs. antihistamine in the small blood vessels? Histamines effects the dilation and increased permeability, allowing substances to leak into tissues. Antihistamine effects the dilation of blood vessels and reduces the increased permeability of blood vessels.
What are the effects of histamine vs. antihistamine in the smooth muscle? Histamine effects salivary, gastric, lacrimal and bronchial secretions. Antihistamines reduce salivary, gastric, lacrimal and bronchial secretions.
What are the effects of histamine vs. antihistamine in the immune system? Histamine-effects mast cells release histamine and other substances resulting in allergic reactions. Antihistamine-binds to histamine receptors, thus preventing histamine from causing a response.
What are antihistamine used for? Nasal allergies, seasonal or perennial allergic rhinitis(hay fever), allergic reactions, motion sickness and sleep disorders.
What effects does antihistamines have on the skin? They reduce capillary permeability, wheal-and-flare formation and itching.
What are some of the side effects of antihistamines? Dry mouth, difficulty urinating, constipation, changes in vision and drowsiness.
What are two examples of tradition antihistamines? Diphenhydramine(Benadryl) and Chlorpheniramine(Chlor-Trimeton)
What are a few examples of antihistamines that were developed to eliminate unwanted side effects mainly sedation that last longer but take longer to work? Fexofendadine(Allegra), Loratadine(Claritin and Centirizine(Zyrtec)
What are some nursing implications for antihistamines? Use caution in increased intraocular pressure, cardiac or renal fosease, hypertension, asthma, COPD, peptic ulcer disease, BPH, or pregnancy.
What is nasal congestion? Excessive nasal secretions, inflamed and swollen nasal mucosa usually caused by allergies and upper respiratory infections like the common cold.
What is the mechanism of action for nasal decongestants? Blood vessels surrounding nasal sinuses.
What is one of the three main types of decongestants? Adrenergics which is the largest group and acts sympathomimetics.
What route is the fastest for relief of congestion? Topical nasal decongestants.
What can happen if topical nasal decongestants are used for a prolonged period of time? It causes rebound congestion, making the condition worse.
What are some of the nursing implications for nasal decongestants? Pt. should avoid caffeine and caffeine-containing products. They should report a fever, cough, or other symptoms lasting longer than a week. They should also be monitored for intended therapeutic effect.
What do antitussives do? Stop coughing.
What are the two types of cough? Productive and nonproductive.
What drugs are used to aid in cough relief? Opioid and nonopioids.
When would opioids and non nonopioids be used? When the cough is non-productive.
What is one of the non-opioid drugs used to suppress a cough? Benzonatate(Tessaion Perles)
What are expectorants? Drugs that aid in the expectoration of mucus, reduce the viscosity or secretion and disintegrate and thin secretions.
What is the mechanism of action of expectorants? Direct stimulation and reflex stimulation.
What are the actions of direct stimulation of expectorants? The secretory glands are stimulated directly to increase their production of respiratory tract fluids.
What are the action of reflex stimulation of expectorants? They cause irritation of the GI tract and loosen and thin the respiratory tract secretions occur in response to this irritation.
What is an example of a reflex stimulation? Guaifenesin
What are some common side effects of Guaifenesin? Nausea, vomiting and gastric irritation.
Created by: hlawrence59
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