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PHOSPHATE
ELECTROLYTES
Question | Answer |
---|---|
What is phosphate? | It is found in bones and is a major factor in the intracellular production of ATP (energy). |
What are the phosphate level? | 3 to 4.5 mg/dL |
What influence phosphate levels? | PTH secretion and calcium concentration. Increase renal excretion of phosphate ions is caused by PTH. Calcium and phosphate have a reciprocal relationship. If calcium levels increase, phosphate levels decrease. |
Hyperphosphatemia | A serum phosphate level above 4.5 mg/dL |
What are the causes of hyperphosphatemia? | Inability to excrete phosphates or excessive ingestion of phosphates. |
What is the clinical presentation of hyperphosphatemia? | The clinical presentation is the same as hypocalcemia. If seizures occur, they are due to hypocalcemia caused by hyperphosphatemia. |
How do you treat hyperphosphatemia? | The objective of therapy is to decrease the serum phosphate level. Administer aluminum hydroxide gels or calcium antacids that combine with phosphate. |
What is hypophosphatemia? | Serum phosphate level < 3 mg/dL. |
What are the cause of hypophosphatemia? | Any factor that increases the cellular uptake to form sugar phosphates will decrease serum levels of phosphate. prolonged hyperventilation, sepsis, diabetic ketoacidosis, malabsorption syndromes, severe diarrhea, chronic alcoholism. |
Clinical presentation of hypophosphatemia? | Complaints of general malaise, anorexia, and vague muscle weakness, hypoxia. |
what is the treatment for hypophosphatemia? | Replace the phosphate. |