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Pediatrics. Ch22.
Drug Interactions
| Question | Answer |
|---|---|
| What is phototoxicity | Skin reactions when exposed to the sun |
| What is it called when medications cause skin reaction when the patient is exposed to the sun | phototoxicity |
| Which drugs are dispensed in dark bottles | Those that decompose when exposed to the air or light |
| How are drugs that decompose when exposed to the air or light dispensed | In dark bottles |
| Which drugs should not be purchased in economy sizes | Those that decompose when exposed to air or light |
| What type of drug interactions should be watched for | Drug/Drug, Drug/Food, Drug Environment |
| What drugs interact with antacids | Digoxin, NSAIDs, Steroids, Tetracycline, Theophylline |
| What drugs interact with barbiturates | Influenza vaccine, Oral contraceptives, Steroids, Theophylline |
| What drugs interact with bleomycin | Oxygen |
| What drugs interact with erythromycin | |
| Phenytoin, Theophylline | |
| What drugs interact with Isoniazid | Antacid, Phenytoin, Valproate |
| What drugs interact with Phenytoin | Alcohol, Antacid, Contraceptives, Steroids, Digoxin, Folic acid, Isoniazid, Theophylline, Tricyclic antidepressants, Valproate |
| When combined with steroids, digoxin, NSAIDs, or Tetracycline, what interaction do antacids have | Decreased absorption |
| What causes decreased absorption when combined with antacids | Digoxin, Isoniazid, NSAIDs, Tetracycline, Steroids |
| What causes increased toxicity when combined with antacids | Theophylline |
| What causes increased toxicity when combined with theophylline | Antacids |
| When combined with barbiturates, which drug has a decreased effectiveness | Oral contraceptives, Steroids, Theophylline |
| When combined with barbiturates, which drug causes barbiturate toxicity | Influenza vaccine |
| When combined with oxygen, what causes increased lung toxicity | Bleomycin |
| What combines with bleomycin to cause increased lung toxicity | Oxygen |
| What drug, combined with erythromycin, has a decreased effect | Phenytoin |
| What drugs decrease the Phenytoin effect | Antacid, Erythromycin, Folic acid |
| What drug, when combined with erythromycin, has an increased toxicity | Theophylline |
| What drug causes theophylline toxicity when combined | Erythromycin |
| What drugs cause Phenytoin toxicity | Isoniazid, Tricyclic antidepressants, Valproate |
| What drugs combine to cause hepatic and CNS toxicity | Isoniazid & Valproate |
| What drug combines with Phenytoin to cause acute toxicity | Alcohol |
| What drug combines with alcohol to cause acute toxicity | Phenytoin |
| What drugs cause a decreased protection of oral contraceptives | Barbituates, Phenytoin |
| What drugs decrease the effectiveness of steroids | Phenytoin, Barbituates |
| What drug decreases the digoxin effect | Phenytoin |
| What drug combines with Phenytoin to decrease the effect of both medications | Theophylline |
| What drug combines with Theophylline to decrease the effect of both medications | Phenytoin |
| What drug interacts with air | Vitamin C |
| How does vitamin C interact with air | It decomposes |
| What drugs interact with sun | imipramine = Chlorothiazide/Diuril, Griseofulvin, Phenothiazines, Tetracyclines, Trofanil |
| What drugs interact with any food to cause a decreased absorption rate | Aminoglycosides, Gentamicin, Penicillin, Tetracycline |
| What drug interacts with high protein and low carb foods to decrease the drugs’ active time in the body | Theophylline |
| How does theophylline react with high protein and low carb foods | Decreases the drug’s active time in the body |
| What foods decrease theophylline’s active time in the body | High protein, Low carb |
| What interacts with MAO inhibitors | Tyramine containing foods |
| What do tyramine containing foods interact with | MAO inhibitors |
| What are examples of tyramine containing foods | Yogurt, Processed meats, Beer |
| What is the interaction of tyramine containing foods and MAO inhibitors | Possible hypertensive crisis |
| What foods decrease the absorption of iron | Starch, egg yolks |
| What foods counteract the effect of antihypertensive drugs | Licorice |
| What decreases the absorption of B12 | Vitamin C |
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