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Chapter 6 Pharm
pharmacodynamics, pharmacology for nurses Adams
| Question | Answer |
|---|---|
| ____________ deals with how medications affect the body responses. | Pharmacodynamics |
| The classic theory about the cellular mechanism by which most medications produce a response is called the ________ theory. | Receptor |
| ______ refers to a drug's strength at a particular concentration or dose, whereas ______ refers to the effectiveness of a drug in producing a more intense response as the concentration is increased. | potency, efficacy |
| A _____ curve is a graphical representation of the actual number of clients responding to a drug action at different doses. | Frequency distribution |
| The median effective dose (ED50) is the dose required to produce a specific therapeutic response in _____% of a group of clients. | 50% |
| The median lethal dose (LD50) is the dose of drug that will be _____ in 50% of a group of animals. | lethal |
| A drug's _____ offers the nurse practical information on the safety of a drug. | therapeutic index |
| A drug that is more potent will produce a therapeutic effect at a _____ dose, compared to another drug in the same class. | lower |
| _____ is the magnitude of maximal response that can be produced from a particular drug. | Efficacy |
| _____ often compete with agonists for the receptor binding sites. | Antagonist. |
| _____ best explains the pharmacodynamic phase of drug administration. | Drug action and the relationship between drug concentration and body responses. |
| You are giving a drug that is unfamiliar to you. You check the drug guide and determine that the average dose for the drug is 100 mg per day. What does this statement mean to you? | The amount of 100 mg will be the effective dosing for about 50% of the population. |
| How would you explain to a client the concept of drug potency. | If you are told to take a drug to control thyroid problems, the drug with the lowest milligram weight is the most potent. |
| When drug molecules bind with cell receptors, what occurs? | Pharmacologic effects of agonism or antagonism occur. |
| A pharmacist tells you that a drug has a high therapeutic index. What does this statement mean to you? | It would take a big error in dosing to create a lethal dose for this client. |
| The nurse hears in a report that the client had an idiosyncratic reaction to a medication. What happened to the client? | An unpredictable and unexplained drug reaction occurred. |
| You are reviewing the terms efficacy and potency with a client who is getting medications for cancer. What statement would best explain this? | the number of cancer cells killed is called efficacy. you are most interested in efficacy in the treatment of your disease. |
| Describe antagonists | They inhibit or block the acton of agonist drugs. |
| You are giving two drugs to a client with a heart problem. One drug works at the beta1-adrenergic receptor and the other at beta2-recptor. How can that be possible? | The drugs are fine-tuned and can affect the different beta-recptor types in specific ways. |
Created by:
myt1462
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