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HYPERNATREMIA
ELECTROLYTES
Question | Answer |
---|---|
SODIUM | The most prevalent cation in the body's extracellular fluid compartment. Normal range 135 meq/L - 145 meq/L. |
Where is Na absorbed in the kidney? | PROXIMAL CONVOLUTED TUBULES (most) |
What affects Na reabsorption? | A decrease in GFR will increase Na reabsortion. |
What is the greatest inhibitor of Na excretion? | ALDOSTERONE |
What are most cases of hypernatremia caused by? | Most cases of hypernatremia are due not to Na disturbances but to fluid disturbances. It may be seen in dehydration. |
What signs to look for with hypernatremia caused by pure water loss or decreased intake? | The hematocrit will be elevated, serum chloride will be above 106 meq/L, urine specific gravity will be greater than 1.025, and urine sodium level will be low. |
What is the most common cause of hypernatremic dehydration? | insufficient ADH secretion. |
What are some causes of hypernatremic dehydration? | Diabetes insipidus, Increased insensible water loss, hypertonic enteral feedings, potassium depletion (from vomiting, diarrhea, or nasogatric sutioning). DM, osmotic diuresis secondary to hyperglycemia. |
What are the clinical presentation of hypernatremia? | DEHYDRATION, DRY STICKY MUCOUS MEMBRANES, THIRST, OLIGURIA, FEVER, TACHYCARDIA, AND AGITATION |
What is the treatment for hypernatremia? | Fluid administration with free water |