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Muscular
Question | Answer |
---|---|
Primary neurotransmitter at the neuromuscular junction is | ACh or Acetylcholine |
As sodium ions enter the muscle cell what happens to the sarcolemma | It becomes Depolarized |
After the sarcolemma reaches the threshold of Depolarized from sodium entering the cell what happens | An Action Potential is generated and propagated over the cell membrane |
Acetylcholine is broken down into what in the synaptic cleft | Acetic acid and Choline by the enzyme Acetylcholinesterase |
How is the Acetylcholine reassembled after being broken down in the synaptic cleft | The Choline is reabsorbed into the synaptic knob where it is combined with acetic acid and placed back in the vesicles |
The influx of Sodium Ions into a cell creates what at the cell membrane | Depolarization |
What is Membrane Potential or Resting Potential | It is the Potential difference of voltage on either side of the cell membrane, |
Most cells have a more negative charge on the inside of the cell membrane than on the outside at the Resting State and is said to be what | Polarized |
The cells membrane potential is referenced at what part of the cell membrane | The difference in voltage between the inside and the outside of the cell at rest |
Why do most cells have a negative charged resting potential or membrane potential | Because of the more negative charge inside of the cell at the membrane |
When the membrane potential becomes more positive than the resting potential the membrane becomes what | Depolarized |
When the membrane potential becomes more negative than the resting potential the membrane becomes what | Hyperpolarized |
Making the cell membrane positive or negative is relative to the resting potential | So if the inside becomes more positive relative to the resting potential the, the membrane potential becomes Positive |
When an Action Potential arrives at the synaptic knob what happens | Causes voltage gated Calcium channels to open which in turns lets the calcium flow into the synaptic knob |
How is Acetylcholine released into the synaptic cleft | After calcium enters the synaptic knob it attaches to the vesicles that contain the ACh and causes them to go through exocytosis with the neuron membrane to release the ACh |
How is a Action Potential generated at the sarcolemma | By the acetylcholine in the synaptic binding to the receptors on the muscle fiber causing the sodium channels to open and allowing sodium to make the inside of the muscle cell more positive , Known as Depolarizing |
The Action Potential at the sarcolemma travels where and creates what action | It propagates across the membrane, down the T-tubules and causes calcium to be released from the sarcoplasmic reticulum |
Calcium released from the sarcoplasmic reticulum travels to where | The Sarcoplasm |
During contraction of a muscle, calcium ions bind to the what | The Troponin Molecule |
What breaks the bond between the Myosin head and Actin | The attachment of a ATP to the Myosin head |
Energy is released on the Myosin head how | By the ATP being broken down into ADP and Phosphate |
When calcium binds to the troponin on the actin what action does this cause | Causes Tropomyosin to move away from the myosin binding site so that the myosin head can bind to the actin |
Excitation is defined as | The action potential in the nerve fiber causing a action potential in the muscle fiber |
What has to be removed before Tropomyosin can cover up the binding sites on the Actin | Calcium , has to be moved back to the Terminal Cisternae |
Define Tetanus or Tetany | Muscle in continual contraction |
Define Twitch | The contraction and relaxation cycle of a muscle |
During Wave Summation what happens | A stimulus arrives at muscle before complete relaxation causing the 2nd contraction to have greater tension the the 1st |
Characteristics of oxidative fibers are | Good for Endurance, Use Aerobic respiration, Red in color, High concentration of Myoglobin |
The immediate supply of ATP for use in muscle contraction is generated what system | Phosphagen system |
When a muscle contracts but does not change length | Isometric |
When a muscle contracts and does change length | Isotonic |
A majority of the muscle fibers in the body are what type of fiber | Fast Glycolytic |
Many myoblast group together to form what | A skeletal muscle fiber |
Multiunit smooth muscle cells are stimulated as a GROUP OR INDIVIDUALLY | Individually |
Single unit smooth muscle cells are stimulated as a group or individually | As a group |
What can cause muscle fatigue , 3 items | Sodium and Potassium imbalances, Insufficient Calcium and a Build up of intracellular Phosphate |
MLCK protein does what | Phosphorylates Mysdin |
Calmodulin protein does what | Binds calcium, Is a calcium binding protein |
MLCP protein does what | Dephosphorylates Myosin |
A Motor Unit is composed of what | A Motor Neuron and ALL of the muscle fibers that it controls |
The A-Band contains which myofilaments | Both Thick and Thin , Creates the Dark band |
The H-Zone contains which myofilaments | Only Thick , this zone disappears during contraction |
The I-Band contains which myofilaments | Only Thin , Creates the Light band |
The Epimysium is composed of what type of tissue | Dense Irregular C.T. |
Smooth muscle is allowed to stay in contraction because of what | Latchbridge Mechanism |
Anaerobic respiration process is for what length of time | Short term use , as in the use of a sprinter/runner |
Concentric Isotonic contraction does what to the muscle | Shortens it |
Eccentric Isotonic contraction does what to the muscle | Lengthens it |
When acetylcholine binds to receptors at the motor end plate and the receptors open what ion enters the muscle fiber sarcoplasm | Sodium ions , This is what will cause a depolarization and cause a action potential at the sarcolemma to release calcium |
The Z-Discs in the sarcomere anchors what | The Thin Filaments |
A sheet of dense irregular connective tissue that is external to the epimysium and separates individual muscles is what | Deep Fascia |
What type of a gated channel are the acetylcholine receptors at the motor end plate | Chemical Gated |