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Exam Three: Actions

TermDefinition
acetazolamide slows movement of hydrogen ions = more na+ and hco3 excreted making blood more acidic and urine more alkalosis
Bumetanide/Furosemide more potent form that blocks cl- pump = excretes na+ and cl- preventing reabsorption
castor oil chemically stimulates reflexes of the gi tract causing inc activity and movement of intestines
cimetidine reduction in gastric acid secretion and pepsin
doxazosin blocks alpha one receptors dilating blood vessels, relaxes bladder/prostate muscles
finasteride blocks the hormone (dht) that causes growth of the prostate, prevents the prostate from getting larger
hydrocholorothiazide blocks cl- pump = excretes na+ and cl- preventing reabsorption
laxatives direct chemical stimulation of the gi tract (castor oil), production of bulk or increased fluid in the lumen (mag citrate/psyllium), lubrication of the intestinal bolus to promote passage through the gi tract (mineral oil)
loperamide slows the motility of the gi through action on the lining of the gi
magnesium citrate cause fecal matter to inc in bulk, pulls fluid into feces, stretches wall causing stimulation and gi movement
mannitol pulls h2o into renal tubule w/out add'l na+ loss, increases osmolarity of blood and renal filtrate
metoclopramide stimulates parasympathetic activity in gi tract inc secretions and motility
mineral oil helps content move more smoothly inc viscosity of feces, causes difficulty with water absorbtion from fecal bolus
non-phenothiazine metoclopramide reduces the responsiveness of the nerve cells in the ctz to circulating chemicals that induce vomiting
omeprazole act at specific secretory surface receptors to prevent the final step of acid production which dec. the level of acid in the stomach
ondansetron block the receptors associated with nausea and vomiting in the ctz and locally
oxybutynin blocks parasympathetic spasms of ut muscles—relaxes
pancrelipase saliva substitute: contains electrolytes and carboxymethylcellulose to act as a thickening agent in dry mouth conditions
pentosan polysulfate sodium heparin-like compound that has anticoagulant effects, adheres to bladder wall and acts as a buffer to control cell permeability preventing irritating solutes in the urine from reaching the bladder walls
phenazopyridine acts as a direct topical analgesic on urinary mucosa
sodium bicarbonate neutralize stomach acid by direct chemical reaction
spironolactone loss of na+ but retains k+, blocks actions of aldosterone, androgen, and testosterone
sucralfate protects duodenal ulcer sites against acid, pepsin, and bile salts
Created by: ahureau
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