Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
MOA and Concerns
Big drug classification with MOA and Concerns
| ACE INHIBITORS (enalaPRIL) | -Prevent the conversion of anigotensin 1 to angiotensin 2, potent vasoconstriction which stimulates aldosterone - monitor b/p and serum K ( Hyperkalemia) |
| CALCIUM CHANNEL BLOCKERS (nifeDIPINE) | -inhibits transport of Ca into the myocardial vascular smooth muscle -inhibits excitation-contraction coupling and subsequent contraction -results in coronary and systemic vasodilation -monitor b/p and pulse *diltiazem and verapamil- different endings |
| BETA-BLOCKER (atenOLOL) | -blocks stimulation of Beta 1(heart) adrenergic receptors and beta 2 (lungs, vascular, and uterine) receptor sites - monitor b/p & heart rate *labetalol & carvedilol- still beta blockers *Carvedilol- Only BETA 1 |
| NITRATES (isosobide diNITRate) | -Increases coronary blood flow by dilating coronary arteries -produces vasodilation -decreases afterload -monitor b/p -headache is common side effect |
| PENICIILINS (amoxiCILLIN) | -Binds to bacterial cell wall resulting in cell death _PRP resists penicillinase, an enzymes which inactivates penicillin -Useful with Gram + and - infections Watch for anaphylaxis |
| CEPHALOSPORINS (CEFazolin) | -Binds to bacterial cell membrane causing cell death; useful with Gram + &- infections; observe for Rashes; Use with caution in people allergic to PCN; 3rd generation; maybe able to take a 2nd or 3rd generation if allergic to 1st generation |
| AMINOGLYCOSIDES (tobraMYCIN) | -inhibits protein synthesis in bacteria at the level of the ribosome; Only gram - infections;OTOTOXIC (tinnitus) & NEPHROTOXIC (watch renal values); Trough- lowest level prior to next dose (10-20 lab value norm); Peak- Highest level after dose is given |
| QUINILONES (ciprofloxACIN) | -inhibits baterial DNA synthesis -used for UTI, lower resp. infections Gram + and - infections |
| TETRACYCLINE (doxyCYCLINE) | -inhibits baterial protein synthesis at the level of the ribosome; take 1 hr before or 2 hours after meals; Ca inhibits absorption; Do NOT take if pregnant or children less than 8; cause permanent staining of teeth |
| MACROLIDE (aziTHROMYCIN) | -inhibits protein synthesis at the bacterial ribosome -same ending as aminoglycosides, plus "thro" MAJOR GI UPSET- Side effect |
| ANTIVIRAL (acycloVIR) | -Interferes with viral DNA synthesis -inhibits viral replication -decreased shedding and reducing healing time |
| ANTIFUNGALS (metronidAZOLE) | -inhibits synthesis of fungal cell wall (work in varying mechanisms to achieve this effect -May be given IV, PO, or topically -Fungal overgrowth found everywhere in the body |
| HISTAMINE H2 ANTAGONISTS (famoTIDINE) | -used in the treatment of gastric disorders -inhibits the action of histamine at the h2 receptor site located mainly in the parietal cells, resulting in less gastric secretions |
| BRONCHODILATORS (thoPHYLLINE) | -used in treatment of airway disease to dilate bronchi and improve oxygentation -used in pneumonia, COPD, aspiration, bronchitis Side Effects: Palpitations, nervousness, insomnia |
| BARBITAL FAMILY (phenoBARBITAL) | -produce CNS depression on many levels -Assess LOC, BP, may have decreased HR |
| BENZODIAZEPINES (lorazePAM;alprazoLAM) | -Depresses the CNS -Produce musculoskeletal relaxation -Monitor: safety, b/p, and LOC |
| STERIOD (methlypredniSOLONE) | -decrease inflammation in various disease processes -must wean from slowly -cause gastric irradiation (give with H2 Blockers) -decrease lymph count -elevated blood sugars |
Created by:
rachrn26
Popular Nursing sets