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Diuretics
Diuretics for Cardiac Drugs
Question | Answer |
---|---|
major clinical indications for these drugs are edema, HF, and hypertension | Diuretics |
most commonly used thiazide diuretic | hydrochlorothiazide |
only thiazide diuretic that can be give IV | chlorothiazide |
Not effective when immediate diuresis is needed | Thiazide |
prescribed for long term management of HF and hypertension | Thiazide |
decrease reabsorption of sodium, water, chloride, and Bicarb in the distal convoluted tubule | Thiazides |
diuretic effects usually occur within 1-2 hours and peak 4-6 hours | Thiazides |
do not use in patients who are allergic to sulfa drugs | Thiazides and Loop |
don't use if pregnant | Thiazides and Loop |
ineffective with decreased renal function | Thiazides |
mild thiazide | HCTZ |
give drug in the AM | Loop and Thiazide |
monitor sodium and chloride | Thiazide |
CL less or equal to 30 ml/min, hold the drug | Thiazide |
K and Mg are lost | Thiazide |
muscle cramps | hypokalcemia |
ppl picking at things | low Mg |
hyperglycemia | Thiazides |
if on Digoxin, you could have toxicity bc of the decreased K | Thiazides |
Calcium is retained | Thiazides |
ingesting licorice | lose K |
ingesting ginko | Increase BP |
can become hypercalcemia | Thiazides |
inhibit sodium and chloride reabsorption in the AL of Henle | Loop |
most filtered sodium is reabsorbed here | ALH |
sodium losing effects are 10 times more effective than thiazides | Loop |
most effective and versatile diuretic | Loop |
diuretic effect occur within 30-60 min. peak in 1-2 hours | Loop |
sodium restriction is required to achieve max effects of the drug | loop |
drug accumulation does not occur even with repeated doses | Loop (the kidneys get rid of the drug) |
immediate diuresis | Loop |
can be used in renal impairment (CCL <30 mL.min) | Loop |
most commonly used loop diuretic and serves as the prototype | Furoemide (Lasix) |
may be used to produce diuresis in some patients who no longer respond to furosemide | Bumetanide (Bumex) |
more potent Loop on a drug-weight basis, and larger doses can be given in small volumes | Bumex |
High ceiling diuretic | Loop (Lasix) |
uric acid levels will rise with this diuretic, so don't give to someone with gout | Loop |
more potent if given IV push, can cause ototoxicity forever | Lasix |
Washes out all electrolytes so hypercalcemia is not a problem | Loop |
if patient does not diures within ________ minutes after IV push, then call they Dr. | Five |
with oral admin. urine flow should increase within _____ min | 30 with Loop |
will cause vasodilation and can be given to patients with renal insufficiencies | Loop |
improve BF by _____% | 40 Loop |
this can be given to person allergic to sulfa | Edecrin 1 gen |
first choice for cancer patients | Loop |
interact with war and coum | Loop |
impacts corticosteroids, amphotericin-b, antihypertensives, and aminoglycosides | Loop |
supplement diet or take supplements for this diuretic | loop |