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Fund - Test 2

Chap. 35 Medications / Terms

QuestionAnswer
medication substance administered for diagnosis, cure, treatment, or relief of symptom or for prevention of disease.
drug aka: medication; illicitly obtained substance such as heroin, cocaine or amphetamines
prescription the written direction for the preparation and administration of a drug
generic name given before a drug becomes officially an approved medication
official name is the name under which it is listed in one of the official publications
chemical name name by which a chemist knows it; this name describes the constituents of the drug precisely
trade name name given by the drug manufacturer. Usually selected to be short & easy to remember
brand name another name for the trade name. May have several trade names.
Pharmacology is the study of effect of drugs on living organisms
Pharmacy is the art of preparing, compounding and dispensing drugs; word also refers to the place where the drug is prepared & dispensed
pharmacist a person licensed to prepare & dispense drugs and make-up prescriptions
pharmacopeoeia (also spelled pharmacopeia) is a book containing a list of products used in medicine, with descriptions of the product, chemical tests for determining identity & purity, and formulas & prescriptions.
Food, Drug & Cosmetic Act requires labels be accurate & all drugs be tested for harmful effects
Durkham-Humphrey Amendment differentiates drugs that can be sold only with a prescription/without prescription and those that cant be refilled without a prescription
Kefauver-Harris Amendment Requires proof of safety & efficacy of a drug for approval
Comprehensive Drug Abuse Prevention and Control Act categorizes controlled subs & limits how often a prescription can be filled; established gov-programs to prevent & treat drug dependence
therapeutic effect (aka: desired effect) primary effect intended; reason the drug is prescribed; what you want to happen
side effect (secondary effect) effect that is unintended; usually predictable & may be either harmless or potentially harmful
adverse effects/reactions the more SEVERE side effects; justify the discontinuation of a drug
drug toxicity results from overdosage, ingestion of a drug inteded for external use & buildup of drug in the blood because of impaired metabolism or extcretion
drug allergy immunologic reaction to a drug; Reacting to the antibodies that are formed by the body when 1st exposed to the foreign substance
anaphylactic reaction SEVERE allergic reaction; Usually occurs IMMEDIATELY after administration of drug; can be FATAL if not treated promptly
drug tolerance exists in person who has unusally low physiologic response to a drug & requires increases in dosage to maintain a given therapeutic effect
cumulative effect increasing response to repeated doses of a drug that occurs when rate od administratio exceeds rate of metabolism or excretion
idiosyncratic effect unexpected & may be individual to that client. Underresponse/overresponse do drug may be idiosyncratic. (unpredictable/unexplainable symptoms in a particular client)
Drug interaction occurs when administration of 1 drug before, at the same time as, or after another drug alters the effect of one or both drugs
Potientiating Effect increased effect(may be additive or synergistic)
Inhibiting Effect decreased effect
Synergistic when 2 different drugs increase the action of 1 or another drug (speeds up)
latrogenic disease diseas caused unintentionally by medical therapy can be due to drug therapy.
drug abuse inappropriate intake of a substance, either continually or periodically
drug dependence is a persons reliance on or need to take a drug or substance
physiologic dependence due to biochemical changes in body tissues, especially the nervous system (tissues come to require the substance for normal functioning)
psychologic dependence emotional reliance on a drug to maintain a sense of well-being, accompanied by feelings of need or cravings for that drug
drug habituation denotes a mild form of psychologic dependence (habit)
illicit drugs (street drugs) those sold illegally. 2 types: drugs unabailable for purchase under any circumstances, such as heroin and drugs normally available with a prescription that are being obtained through illegal channels(usually taken to feel happy/relaxed)
Probenecid Blocks excretion of penicillin
drug misuse improper use of common medications in ways that lead to acute & chronic toxicity (OTC & prescriptions)
half-life describes action of drug in the body; time interval required for the body's elimination processes to reduce the concentration of the drug in body by 1/2.
peak plasma level when orally administered drug is absorbed from gastrointestinal tract into blood plasma, concentration in plasma increases until elimination rate equals rate of absorption.
Drug actions onset of actionpeak plasma leveldrug half-lifeplateau
onset of action time after administration when body initially responds to the drug
peak plasma level highest plasma level achieved by a single dose when the elimination rate of a drug equals the absorption rate
plateau a maintained concentration of a drug in the plasma during a series of scheduled doses
pharmacodynamics process by which a drug changes the body
receptor usually protein, is located on teh surface of a cell membrane or within the cell
agonist drug that produces the same type of response as they physiologic or endogenous substance
antagonist drug that inhibits cell function by occuyping receptor sites (prevents natural body substances from activating the functions of the cell by occupying receptor sites)
pharmacokinetics study of absorption, distribution, biotransformation & excretion of drugs
absorption process by which a drug passes into bloodstream
distribution transportation of a drug from its site of absorption to its site of action
biotransformation (detoxification/metabolism) process by which a drug is converted to a less active form
metabolites products of biotransformation; 2 types: active & inactive
first-pass effect oral drugs 1st pass through the liver & are partially metabolized prior to reaching the target organ
Created by: dbrust
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