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Stack #197078
Phcc phi
| Drugs | Classification | Action | Adverse/ Side Effect | Contridication | Rx Anagonist |
|---|---|---|---|---|---|
| Gentamycin(Garamycin) | Therapeutic: anti-infectives Pharmacologic: aminoglycosides | Inhibits protein synthesis in bacteria at level of 30S ribosome. Therapeutic Effects: Bactericidal action. Spectrum: Most aminoglycosides notable for activity against: P. aeruginosa, Klebsiella pneumoniae, E.coli, Proteus, Serratia, Acinetobacter, Staph | CNS: ataxia, vertigo. EENT: ototoxicity (vestibular and cochlear). GU: nephrotoxicity. GI: Neomycin: diarrhea, nausea, vomiting. F and E: hypomagnesemia. MS: muscle paralysis (high parenteral doses). Neuro: ↑ neuromuscular blockade. Resp: apne | Hypersensitivity to aminoglycosides Most parenteral products contain bisulfites and should be avoided in patients with known intolerance Products containing benzyl alcohol should be avoided in neonates Intestinal obstruction (neomycin only). Use Ca | |
| Tetracycline | Therapeutic: anti-infectives Pharmacologic: tetracyclines | Inhibits bacterial protein synthesis at the level of the 30S bacterial ribosome. Therapeutic Effects: Bacteriostatic action against susceptible bacteria. Spectrum: Includes activity against some gram-positive pathogens:: Bacillus anthracis, Clostridium | CNS: benign intracranial hypertension (higher in children)minocycline: dizziness. EENT: minocycline--, vestibular reactions. GI: diarrhea, nausea, vomiting, esophagitis, hepatotoxicity, pancreatitis. Derm: photosensitivity, rashesminocycline: pigmen | Hypersensitivity Some products contain alcohol or bisulfites and should be avoided in patients with known hypersensitivity or intolerance OB: Pregnancy (risk of permanent staining of teeth in infant if used during last half of pregnancy) Lactation | |
| Septra | Therapeutic: anti-infectives, antiprotozoals Pharmacologic: folate antagonists, sulfonamides | Combination inhibits the metabolism of folic acid in bacteria at two different points. Therapeutic Effects: Bactericidal action against susceptible bacteria. Spectrum: Active against many strains of gram-positive aerobic pathogens including: Streptococc | Hypersensitivity to sulfonamides or trimethoprim Megaloblastic anemia secondary to folate deficiency Severe renal impairment Pregnancy, lactation, or children <2 mo (can cause kernicterus in neonates). Use Cautiously in: Impaired hepatic or renal | CNS: fatigue, hallucinations, headache, insomnia, mental depression. GI: PSEUDOMEMBRANOUS COLITIS, HEPATIC NECROSIS, nausea, vomiting, diarrhea, stomatitis, hepatitis, cholestatic jaundice. GU: crystalluria. Derm: TOXIC EPIDERMAL NECROLYSIS, rashes, | |
| Ceftin | Therapeutic: anti-infectives Pharmacologic: second-generation cephalosporins | Bind to bacterial cell wall membrane, causing cell death. Therapeutic Effects: Bactericidal action against susceptible bacteria. Spectrum: Similar to that of first-generation cephalosporins but have ↑ activity against several other gram-negative pathoge | Contraindicated in: Hypersensitivity to cephalosporins Serious hypersensitivity to penicillins. Use Cautiously in: Renal impairment (↓ dose/↑ dosing interval recommended for: cefotetan if CCr ≤ 30 ml/min, cefoxitin if CCr ≤ 50 ml/min, cefprozil if | CNS: SEIZURES (HIGH DOSES). GI: PSEUDOMEMBRANOUS COLITIS, diarrhea,, cramps, nausea, vomiting. Derm: rashes, urticaria. Hemat: agranulocytosis, bleeding (↑ with cefotetan and cefoxitin), eosinophilia, hemolytic anemia, neutropenia , thrombocytopenia | |
| Penicillin | Therapeutic: anti-infectives Pharmacologic: penicillins | Bind to bacterial cell wall, resulting in cell death. Therapeutic Effects: Bactericidal action against susceptible bacteria. Spectrum: Active against: Most gram-positive organisms, including many streptococci (Streptococcus pneumoniae, group A beta-hemo | Previous hypersensitivity to penicillins (cross-sensitivity may exist with cephalosporins and other beta-lactams) Hypersensitivity to procaine or benzathine (procaine and benzathine preparations only) Some products may contain tartrazine and should be | CNS: SEIZURES. GI: diarrhea, epigastric distress, nausea, vomiting, pseudomembranous colitis. GU: interstitial nephritis. Derm: rashes, urticaria. Hemat: eosinophilia, hemolytic anemia, leukopenia. Local: pain at IM site, phlebitis at IV site. Mis | |
| Demerol | Therapeutic: opioid analgesics Pharmacologic: opioid agonists | Binds to opiate receptors in the CNS. Alters the perception of and response to painful stimuli, while producing generalized CNS depression. . Therapeutic Effects: Decrease in severity of pain. | CNS: SEIZURES, confusion, sedation, dysphoria, euphoria, floating feeling, hallucinations, headache, unusual dreams. EENT: blurred vision, diplopia, miosis. Resp: respiratory depression. CV: hypotension, bradycardia. GI: constipation, nausea, vomi | Hypersensitivity Hypersensitivity to bisulfites (some injectable products) Pregnancy or lactation (chronic use) Recent (14-21 days) MAO inhibitor therapy. Use Cautiously in: Head trauma Increased intracranial pressure Severe renal, hepatic, | |
| transdermal nitroglycerin patch | Therapeutic: antianginals Pharmacologic: nitrates | Increases coronary blood flow by dilating coronary arteries and improving collateral flow to ischemic regions. Produces vasodilation (venous greater than arterial). Decreases left ventricular end-diastolic pressure and left ventricular end-diastolic v | CNS: dizziness, headache, apprehension, restlessness, weakness. EENT: blurred vision. CV: hypotension, tachycardia, syncope. GI: abdominal pain, nausea, vomiting. Derm: contact dermatitis (transdermal or ointment). Misc: alcohol intoxication (la | Hypersensitivity Severe anemia Pericardial tamponade Constrictive pericarditis Alcohol intolerance (large IV doses only) Concurrent use of sildenafil. Use Cautiously in: Head trauma or cerebral hemorrhage Glaucoma Hypertrophic cardiomyopa | |
| Midazolam (Versed) | benzodiazepines antianxiety agents, sedative/hypnotics | Acts at many levels of the CNS to produce generalized CNS depression. Effects may be mediated by GABA, an inhibitory neurotransmitter. Therapeutic Effects: Short-term sedation. Postoperative amnesia | *CAPITALS indicate life threatening; underlines indicate most frequent. CNS: agitation, drowsiness, excess sedation, headache. EENT: blurred vision. Resp: APNEA, LARYNGOSPASM, RESPIRATORY DEPRESSION, bronchospasm, coughing. CV: CARDIAC ARREST, a | Contraindicated in: Hypersensitivity Cross-sensitivity with other benzodiazepines may occur Shock Comatose patients or those with pre-existing CNS depression Uncontrolled severe pain Products containing benzyl alcohol should not be used in neo | Romazicon |
| Atropine Sulfate | Therapeutic: antiarrhythmics anticholinergics, antimuscarinics | Inhibits the action of acetylcholine at postganglionic sites located in: Smooth muscle, Secretory glands , CNS (antimuscarinic activity). Low doses decrease: Sweating, Salivation, Respiratory secretions. Intermediate doses result in: Mydriasis (pupill | CNS: drowsiness, confusion, hyperpyrexia. EENT: blurred vision, cycloplegia, photophobia, dry eyes, mydriasis. CV: tachycardia, palpitations, arrhythmias. GI: dry mouth, constipation, impaired GI motility. GU: urinary hesitancy, retention, impoten | Contraindicated in: Hypersensitivity Angle-closure glaucoma Acute hemorrhage Tachycardia secondary to cardiac insufficiency or thyrotoxicosis Obstructive disease of the GI tract. Use Cautiously in: Intra-abdominal infections Prostatic hyper | |
| Dantrolene (Dantrium) | skeletal muscle relaxants (direct acting) | Acts directly on skeletal muscle, causing relaxation by decreasing calcium release from sarcoplasmic reticulum in muscle cells. Prevents intense catabolic process associated with malignant hyperthermia. Therapeutic Effects: Reduction of muscle spastic | CNS: drowsiness, muscle weakness, confusion, dizziness, headache, insomnia, malaise, nervousness. EENT: excessive lacrimation, visual disturbances. Resp: pleural effusions. CV: changes in BP, tachycardia. GI: HEPATOTOXICITY, diarrhea, anorexia, cr | No contraindications to IV form in treatment of hyperthermia Pregnancy and lactation Situations in which spasticity is used to maintain posture or balance. Use Cautiously in: Cardiac, pulmonary, or previous liver disease Women, patients >35 yr (i |
Created by:
blackneckphi
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