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N112 Antidepressants

N112 - Antidepressants for final

QuestionAnswer
What are the different categories of antidepressants? Tricyclic - TCAs, Selective serotonin reuptake inhibitors - SSRIs, Monoamine oxidase inhibitors - MAOIs, Heterocyclic/Tetracyclics - 2nd Generation antidepressants.
What are they used for? Affective disorder - depression, smoking cessation - Wellbutrin.
What are the actions of antidepressants? Antidepressants cause adaptive changes in the serotonin & norepinephrine receptor systems and help to restore these levels within the nerves.
What are TCA side effects? Drowsiness/sedation, dry mouth, N/V, arrhythmias, impotence, constipation, altered libido.
What are SSRI & 2nd generation side effects? Insomnia, weight gain, sexual dysfunction, GI symptoms, Serotonin syndrome - delirium, agitation, tachycardia, sweating, myoclonus - involuntary twitching & shivering.
What are MAOI side effects? Orthostatic hypotension, hypertensive crisis, anorexia, dry mouth & impotence.
What are some patient teachings for antidepressants? Take with meals to avoid GI upset, drug may take 4-6 weeks to obtain max response, do not stop taking abruptly, avoid alcohol. Pts taking MAOIs should avoid tyramine - in aged cheese, smoked meats, red wines - potential for hypertensive crisis.
Created by: jrb265
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