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W13 Analgegics
Question | Answer |
---|---|
Main use of skeletal muscle relaxant | Prevent/interrupt muscle spasm associated with spastic disease, spinal cord damage or overexertion of muscles |
Types of muscle relaxants | Peripheral and central; Peripherally acting works within the muscle and centrally acting work within the spinal cord; |
Muscle relaxants and asthma pt | Peripheral acting can be dangerous for patient with asthma because it increase bronchial secretion and produce histamine release |
Effects of muscle relaxants on CNS | Lethargy, decreased mental alertness, dependence |
Where do opioid come from? | Naturally occurring plant substance opium OR synthetic substances that produce the same pharmacologic effects as opium |
Difference btw opiate and opioid | OID is synthetic, ATE is natural |
Analgegics OPIATES | Hydrocodone, Codeine (antitussive), Morphine (analgesic) |
Define, Uses, Cautions, Pt teaching for NSAID’s | Aspirin, Ibuprophen, Naproxen, Mild to Moderate pain,anti-inflammatory, Allergy, GI Upset, Take with food, Salicylates are platelet aggregator inhibitors (baby aspirin), prevent Heart attack. |
2 elements composing pain | localized stimulation of peripheral nerves and recognition of pain within the CNS |
Symptoms of pain | Subjective, pt said he’s in pain, objective, redness, inflammation, warm to touch |
Common psychological responses to pain | Grimacing, gardening, not participating in activities with mvt, depression |
Pain meds for mild to moderate | Non-Narcotics. NSAIDs with Narcotic can be used to reduce inflammation |
Pain meds for moderate to severe | Narcotics |
Describe some concerns about narcotics analgesics | Pt seeking meds, CNS depression lead to other pb, constipation, dependence |
What schedule are most narcotics used for pain control? | Schedule 2, One prescription, no refill w/o new written prescription, Heroin is Schedule 1 |
Common SE for opiates | Rash, respiratory depression (drop respiration rate) |
Common pharmacological effects of opiates | Change in mental alertness, sedation (μ, κ), Depression of respiratory centers (µ) |
Narcotic analgesics: describe why respiratory depression is an important consideration? | It is common, can affect oxygenation of pt, drug tolerance, when taking a lot, check respiratory status first. |
Naloxone | Narcotic Antagonist, Agonist, used for Overdose of opioid |
Platelet aggregation inhibition | Salicylate cause Platelet aggregation inhibition |
Redness of the skin caused by dilatation and congestion of the capillaries, often a sign of inflammation or infection | Erythema |
Capable of relieving or suppressing coughing | Antitussive |
Reduce elevated body temperature (fever) | Antipyretic |
Preventing or reducing inflammation | Anti inflammatory |
A medication that reduces or eliminates pain | Analgesic |
NSAIDs | NSAIDs |
Occurs as a result of taking a drug and receive less therapeutic effect of the drug over the time | Drug tolerance |
What to do when drug tolerance occurs | Increase the dosage |
Combination of psychological and physical factors if the patient doesn’t receive the drug | Drug dependency |
No more able to perform regular life w/o drug | Addiction |
Difference between tolerance, dependence, addiction | Tolerance = occurs when drug abuse, less therapeutic effect, Dependence = physiological and psychological effect if not receiving drug, Addiction = No more able to perform regular life w/o drug |
Use your graph to describe properties of narcotic analgesics | Pain relieve, but also antitussives (prevent coughing) |
Dextromethorphan: Why is it special? Uses? | Only Narcotic OTC antitussive |
Food products containing salicylates | Peppers, raisins, cherries, Cheese, pt high risk for bleeding shouldn’t use these (hemophilia, surgery pt, esophageal varices) |
Why do so many analgesics cause GI Upset? | They are prostaglandin inhibitors, they decrease the mucus that the prostaglandin produces |
Which non narcotics analgesic is best for asthma clients? | Acetaminophen (Tylenol) |
Platelet aggregation inhibition. Which classes? | Salicylates (Aspirin) |
Sign of inflammation | Heat, redness (erythema), swelling, and pain |
Overdose ASA / Tylenol causes what? Assessment findings? | Both cause hepatic cqces (liver), acidosis; Reyes syndrome, respiratory depression, listen to weezing in lung, Tinnitus, lethargy, coma. Assess and figure out how much drugs, and what type |
Rare disorder occurring primarily in children after a viral illness and associated with aspirin usage, characterized by vomiting, swelling of the brain, and liver dysfunction | Reye syndrome |
Naproxen (Aleve) and Motrin (Ibuprofen) | NSAIDs, Analgesic, Anti-pyretic and anti-inflammatory; Naproxen last up to 12 hours, Ibuprofen up to 4 hours |
Cox 2 inhibitor | NSAIDs used for bones and joins problems (osteoarthritis and rheumatoid arthritis) |
Acetaminophen (Tylenol) | Analgegic, anti-pyretic, reyes syndrome (ASA too) |
Special inflammatory condition in which uric acid deposits in the joint fluid of the toes, knees, or kidneys because uric acid is overproduced or not efficiently excreted | Gout |
Colchicines | Treat gout |
Dextromethorphan | Only Narcotic OTC as antitussive |
Naloxone | Narcotic Antagonist, Agonist, used for Overdose of opioid |
Motrin/Ibuprophen | OTC NSAIDs |
Methadone | Opiate, to treat addiction to morphine or heroin |
Acetylsalicylic acid | ASA, 4 A of Aspirin, Anti-inflammatory, Anti-pain, Anti-pyretic, Anti-platelet aggregation |
Effects of aspirin and salicylates | Reduce fever and pain, increase peripheral blood flow (vasodilation), increase sweating, and prophylactically inhibit clotting (Platelet aggregator inhibitor) |
Colchicines | Treat gout |