Question | Answer |
How might you get a granulocyte defect? | Through chemotherapy, or congenitally |
What are the pathogens that could result from a PMN deficiency? | E. Coli, Pseudomonas, Klebsiella, Staph Aureus, Aspergillosis |
What are the consequences of PMN defect? | 1) Translocation of gut flora 2)Bacteria from colon enter bloodstream (gram negative enterics, anaerobes) 3)Bacteria from mouth enter bloodstream (Strep Viridans) |
What are the causes of T cell mediated defect? | STeroids, Chemo, AIDS |
What might you get from T cell mediated defects? | AIDS like - PCP, mycobacterial, toxo, herpes, fungus, |
Which are the three groups of fungi that effect human health? | Candida, Aspergillus, Dimorphic/geographic fungi |
What microbes may exploit an absent spleen? | Pneumococcus, N. Menngitidis, Klebsiella, H. Influenza, Varicella |
A surgery/catheter/radiation may put you at risk for what? | Local flora becoming invasive. |
After a bone marrow transplant, you are at risk for what? | Pneumonia, Viral(HSV, CMV, Adenovirus, VZV), Fungal (Candida, Aspergillus), Gram +ve, -ve, Neutropenia, graft veruses host acute/chronic |
Diabetes puts you at risk for what? | Diabetic foot |
Pregnancy may put you at risk for what? | Listeriosis, Hep E, TB, |
Dialysis puts you at risk for what? | Hep B and C, |
Alcohol puts you at risk for what? | Pneumonia |
Cigarettes put you at risk for? | Pneumonia, bronchitis, cancer, death, bad skin, bad breath, secondary cancer |
Inhaled and IV drugs puts you at risk for? | Pneumonia, endocarditis, hepatitis, HIV |