Question | Answer |
Hormones | made up mostly proteins eg: insulin, some hormones are steroids eg: cortisol |
proteins | digested in the stomach |
why are some hormones not taken orally | orally they will be ineffective, other routes of administration are required eg: nasal spray, injection |
anti-diuretic hormone hyposecretion of ADH uses: which drug used & ROA | desmopressin-DDAVP-nasal spray, TU: diabetes insipidus |
what drug is used for fertility and MOA: | clomiphene-clomid, serophene MOA:increases output of FSH & LH by the pituitary |
what are some other suitable routes of administration | nasal spray or injection |
what drug is used for treatment of endometriosis= danazol-cyclomen | AE: virilism eg: deep voice, facial hair |
what drug prohibits lactation or milk production? what else drug used for? | bromocriptine-Parlodel used to treat wear off symptoms of Parkinson's disease |
Thyroid gland | iodine is required for T3&T4 production |
thyroid gland/hyposecretions Name 2 drugs used for hypothyroidism are they interchangeable | Levothyroxine-Eltroxin & levothyroxine-synthroidNB:synthroid & Eltroxin are not interchangeable |
Name a drug used for hyperthyroidism while awaiting surgery? | Propylthiouracil-Propyl-thyracil |
Corticosteroids are | derived from lipids, needs monitoring because natural hormones won't be produced, delayed healing, thinning bone and skin should be decreasing doses, gradually wearing off, should be used short term and supportive only. |
fill in the blank ? | The pituitary produces the hormone ACTH which stimulates the ADRENAL glands to produce these hormones |
Name 3 corticosteroids by their duration of action first | short action hydrocortisone-cortef, cortisone acetate-cortone |
Name 3 corticosteroids by their duration of action Second | intermediate acting prednisone-deltasone, prednisolone-pediapred(liquid) |
Name 3 corticosteroids by their duration of action third | long acting betamethasone-betnesol, dexamethasone-decadron |
3 corticosteroids by their duration of action: | may be used parenterally, orally, as nasal spray. Nasal sprays and topical use have least AE. |