| Question |
Answer |
| asd | sd |
| GENERIC NAME | DILTIAZEM |
| BRAND NAME | Cardizem |
| CLASS | Calcium Channel Blocker, Calcium antagonist |
| MECHANISM OF ACTION | Inhibits calcium ion influx across cell membranes during depolarization,decreases SA&AV conduction,dilates coronary&peripheral arteries.Slows the rapid ventricular rate associated with a-fib and a-flutter,&reduces coronary&peripheral vascular resistance. |
| INDICATIONS | Rapid ventricular rates associated with atrial fibrillation and atrial flutter, and for PSVT refractory to adenosine. |
| CONTRAINDICATIONS | Hypotension(less than 90 mmHg systolic), Acute Myocardial infarction, Cardiogenic shock, Ventricular tachycardia or wide-complex VT of unknown origin, Second or third-degree AV block,(WPW) syndrome, Sick Sinus syndrome, Beta Blocker Use |
| ADVERSE REACTIONS | hypotension, Bradycardia, heart block, chest pain, and Asystole, N/V, headache, fatigue, drowsiness |
| NOTES ON ADMINISTRATION | None |
| INCOMPATABILITIES/DRUG INTERACTIONS | Avoid use in patients with poison- or drug-induced tachycardia. Calcium chloride can be used to prevent the Hypotensive effects of this drug and treat patients with a calcium channel blocker overdose. |
| Beta blocker use. | |
| DOSE/ROUTE, Adult Dosage, Initial | 0.25 mg/kg IVP (usually 20 mg) administered over 2 minutes.If response is inadequate, repeat in 15 minutes; 0.35 mg/kg IVP administered over 2 minutes |
| Adult Maintenance infusion | 5.0 to 15 mg/hr |
| Pediatric Dosage | The safety of this drug for use in children has not been established. |
| ONSET OF ACTION | IV - immediately |
| PEAK EFFECTS | IV - 2 hours or less |
| DURATION OF ACTION | IV - 4 to 6 hours |
| AZ DRUG BOX SUPPLY RANGE | 25 mg,10 mg |
mr. charles11
