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Atropine! Hangman

 
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Question Answer
GENERIC NAME   None  
BRAND NAME   Atropine  
CLASS  Anticholinergic agent  
MECHANISM OF ACTION  Parasympatholytic; Inhibits action of acetylcholine at postganglionic parasympathetic neuroeffector sites. Increases HR in life threatening bradyarrhythmias.  
INDICATIONS   Hemodynamically unstable Bradycardia, Asystole, Bradycardic (<60 beats a minute) PEA, Organophosphate poisoning, bronchospastic pulmonary disorders.  
CONTRAINDICATIONS   Tachycardia, Hypersensitivity, unstable cardiovascular status in acute hemorrhage and myocardial ischemia, narrow-angle glaucoma.  
ADVERSE REACTIONS  Headache, dizziness, Palpitations, N/V, Tachycardia, arrhythmias, anticholinergic effects (blurred vision, dry mouth, urinary retention), paradoxical Bradycardia when pushed slowly or at low doses, flushed, hot, dry skin.  
NOTES ON ADMINISTRATION  Pregnancy category C, Moderate doses may cause pupil dilation.  
INCOMPATABILITIES/DRUG INTERACTIONS  Potential adverse effects when administered with digoxin, cholinergics, physostigmine. Effects enhanced by antihistamines, procainamide, quinidine, antipsychotics, benzodiazepines, and antidepressants.  
DOSE/ROUTE; Adult,Asystole and Bradycardic PEA   1mg IV/IO push may repeat every 3-5 minutes up to 3 doses.  
DOSE/ROUTE, ADULT, Unstable Bradycardia   0.5 mg IV/IO every 3-5 minutes not to exceed 3mg total.  
DOSE/ROUTE, ADULT, Organophosphate Poisoning   Extremely large doses (2-4mg or higher)  
DOSE/ROUTE,PEDEATRIC   0.02 mg/kg IV/IO push. May double for second dose. Minimum single dose is 0.1 mg.  
DOSE/ROUTEChild   0.02 mg/kg IV/IO push. May double for second dose. Maximum single dose in child is 0.5mg. Max total dose is 1mg  
DOSE, Adolescent single dose   1mg and total dose 2mg.  
ONSET OF ACTION  Immediate  
PEAK EFFECTS  Rapid to 1-2 minutes  
DURATION OF ACTION  Duration 2-6 hours  
AZ DRUG BOX SUPPLY RANGE  (4)prefilled 1mg syringes. Total 4mg (1)8mg Multidose vial.