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Histology-Endocrine Hangman

 
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Question Answer
which endocrine organ is the president?  hypothalamus  
which endocrine organ is the vice-president?  pituitary  
which part of the pituitary is anterior?  adenohypophysis  
what is another name for the adenohypophysis?  pars distalis  
what are the 3 cell types in the adenohypophysis?  basophils, acidophils, chromophobes  
which is smaller, basophils or acidophils?  acidophils  
what are the three basophilic cells? what do they secrete? where are they found?  thyrotropes, corticotropes, gonadotropes; tsh, acth, fsh & lh; adenohypophysis  
what are the two acidophilic cells? what do they secrete? where are they found?  somatotropes and mammotrophs; growth hormone and prolactin; adenohypophysis  
what does acth do? where does this have its effect?  stimulates glucocorticoid synthesis; adrenal zona fasiculata and reticularis  
what does tsh do? where does this have its effect?  stimulates production of thyroid hormones; follicular cells  
what does fsh do? where does this have its effect?  stimulates follicle development and androgen-binding production in sertoli cells; ovaries and testes  
what does lh do? where does this have its effect?  stimulates steroidogenesis in ovarian follicles, corpus leuteum, and leydig cells (testosterone); ovary and testes  
what are the support cells for the neurohypophysis? what cell provides these with materials to do so?  pituicytes; herring bodies  
what two hormones are produced in the neurohypophysis? what do these hormones do?  adh and oxytocin; stimulates water resorbtion in the renal medulla; stimulates smooth muscle contraction (causes contractions and milk ejection)  
what are the two cell types of the thyroid?  follicular and parafollicular  
which cells are also called c cells? what do they produce?  parafollicular; calcitonin  
what cells are also called principle or epithelial cells? what do they produce? what kind of epithelium?  follicular; T3 and T4; simple cuboidal  
what is the pink in the thyroid glands?  inactive hormone (iodinated thyroglobulin)  
what disorder is the result of circulating immunoglobulin that binds and perpetually activates the tsh receptor?  hyperthyroidism (grave's disease)  
what disease is the result of autoimmune destruction of thyroid?  hypothyroidism (hasimoto's disease)  
describe morphology of hashimoto's disease?  infiltration of lymphs and plasma cells, may see germinal centers  
what does calcitonin do?  calcitonin suppresses bone resorption by inhibiting osteoclast activity  
thyroid produces more t3 or t4? which is more potent?  t4; t3  
t3 or t4, which is converted to the other in the liver?  t4 converted to t3  
where are parathyroid glands found and how many?  on posterior thyroid; 4  
what cells are in the parathyroid gland? what is their function?  principle cells and oxyphil cells; secretes parathyroid hormone, which increases osteoclast activity; oxyphil cells is unknown  
parathyroid principle cells are sometimes called what?  chief cells  
what does the zona glomerulosa secrete? what does it regulate?  aldosterone (mineralocorticoids); blood pressure via salt resorbtion  
what does the zona fasiculata secrete? what does it regulate?  glucocorticoids (cortisol and corticosterone); carbohydrate metabolism to raise blood glucose  
what does the zona reticularis secrete? what does it regulate?  androgens DHEA and androstenedione; sex hormones  
what does the adrenal medulla secrete?  norepinephrine and epinephrine  
where is the pineal gland located? what is its function?  near ventricles of brain; controls 24 hour cycles and hormonal levels, senses light and dark  
what are the 3 cell types of the pancreas? what do they produce? what are their effects?  alpha, beta, delta; glucagon, insulin, somatostatin; raise glucose levels, lower glucose levels; inhibit release of insulin and glucagon  
where do enteroendocrine cells exist?  in pits of GI glands  
hypersecretion of cortisol leads to what disease?  cushing's syndrome  
hyposecretion of adrenal cortex leads to what disease?  addison's disease