| Question | Answer |
| Hemicholinium | Stops Ach synthesis... by blocking re uptake of choline |
| Vesamicol | Prevents storage of Ach |
| Botulinus toxin | blocks release of Ach |
| Latrotoxin | Causes explosive release of Ach |
| Physostigmine | inhibits Ach metabolism |
| Muscarine | Activation of the postsynaptic receptor binding(muscuranic) |
| Atropine | Blockade of the postsynaptic receptor binding(muscuranic) |
| Nicotine | Activation of the postsynaptic receptor binding(nicotinic) |
| Mecamylamine | Blockade of the postsynaptic receptor binding(nicotinic- neuronal) |
| Tubocurarine | Blockade of the postsynaptic receptor binding(nicotinic- muscular) |
| Where are nicotinic neuronal found? | Ganglionic neurons, adrenal medulla, some
presynaptic cholinergic terminals, CNS
neurons. |
| Where are nicotinic muscular found? | Skeletal neuromuscular endplates. |
| Where are M1 Receptors found? | Ganglionic neurons, some presynaptic
terminals, CNS neurons. |
| Where are M2 Receptors found? | Myocardium, presynaptic terminals,
ganglionic neurons, some smooth muscle,
CNS neurons. |
| Where are M3 Receptors found? | Smooth muscle, exocrine glands, vascular
endothelium, CNS neurons. |
| Metyrosine | Blocks NE synthesis |
| Reserpine | Prevents storage OF ne |
| Guanethidine | Prevent the release of NE |
| Tyramine
Amphetamine | Promote release of NE |
| Cocaine,
Tricyclic antidepressants | Inhibit reuptake of NE |
| MAO inhibitors | inhibit NE metabolism |
| Epinephrine | Alpha-1 and Alpha-2 receptor
binding receptor activation |
| Prazosin | Alpha-1 receptor
binding receptor block |
| Yohimbine | Alpha-2 receptor
binding receptor block |
| Dobutamine | Beta-1 receptor
binding receptor activation |
| Metoprolol | Beta-1 receptor
binding receptor blockade |
| Albuterol | Beta-2 receptor
binding activation |
| Butoxamine | Beta-2 receptor
binding block |
