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Pharm test 30 apr
10 drugs and calculations
Drug | MOA: | Effect: | Indications: |
---|---|---|---|
Albuterol | Selective beta-2 agonist that stimulates adrenergic receptors of the sympathomimetic nervous system resulting in smooth muscle relaxation in the bronchial tree and peripheral vasculature. | Smooth muscle relaxation | Bronchospasm, Asthma |
Atropine | Blocks acetylcholine at muscarinic receptor sites | Blocks parasympathetic response and allows the sympathetic response to take over; resulting in the increase of cardiac output and the drying of secretion sludge | Symptomatic bradycardia, Asystole, PEA |
Diazepam | Acts on parts of the limbic system, the thalamus, and hypothalamus producing calming effects; Potentiates effects of inhibitory neurotransmitters. | Increased seizure threshold | Status epilepticus, transient analgesia, delirium tremens. |
Diphenhydramine | Blocks cellular histamine receptors, but does not prevent histamine release. | Decreases capillary permeability and decreases vasodilation, as well as prevention of bronchospasm. | Anaphylaxis, Phenothiazine reactions, Antiemetic |
Epinephrine | Stimulates Alpha, B1 and B2 receptor sites | A- vasoconstriction; B1- Inc. HR, Inc. FOC, Inc. CV; B2- Smooth muscle relaxation | Anaphilaxis, Reactive airway disease, Pulseless. |
Furosemide | Inhibits electrolyte reabsorption in the ascending Loop of Henle | Diuresis, venodilator | Pulmonary edema, CHF, Cerebral edema |
Ipratropium Bromide | Blocks acetylcholine at muscarinic receptor sites | Bronchodilator | Bronchospasm associated with COPD |
Methylprednisolone Sodium Succinate | stabilizes cellular and intracellular membranes | Anti-inflammatory | Reactive airway disease, Burns potentially involving the airway |
Sodium Bicarbonate | Buffers H+ and increases pH | Increases pH | Pre-existing metabolic acidosis, Overdose of aspirin, Cyclic antidepressant overdose, Cardiac arrest after other interventions and ventilation is adequate |
Activated Charcoal | Physical binding (adsorption) of poisons from the GI tract. | prevents/reduces systemic absorption of poisons | Oral ingestion of poisons |