click below
click below
Normal Size Small Size show me how
q-bank 1
q-bank
Question | Answer |
---|---|
free ribosomes function? | synthesis of cytosol protein |
attached ribosome function? | synthesis of cell membrane protein |
antibody on membranous nephropathy? | PLA2R |
Dobutamine? | B1 adrenergic (inc, ionotropy and chronotropy) also used instead of exercise stress test, checks for supply-demand mismatch. |
growth factor acts on (igf-1)? | Jak-stat pathway |
Drug for motion sickness. S/E? | Scopolamine (anti-muscuranic/anti-cholinergic) causes blurry vision, dry mouth, urinary retention, constipation |
MEN 1 | (THINK OF FLYNN RIDER-TANGLED) He had a Pan (pancreas), which he hit on head (pituitary adenoma) and he was HYPER around (para) rapunzel (hyperparathyroid) |
MEN 2 | (THINK OF MAD FEW MEN) mad(medullary thyroid cancer), few (pheochromocytoma) and 2A (alpha are hyper so parathyroid hyperplasia) and 2B (Beta men are thin so marfanoid habitus and mucosal neuroma) |
hypo ca+2 and hypo mg+2 in a ganciclovir-resistant patient, what is the drug? | Foscarnet (pyrophosphate analogue) |
Difference between neurocysticercosis and toxoplasmosis and bartonella's disease? | Neurocysticercosis= seizures and cysts (scolex) eggs ingested from stool Toxoplasmosis= in immunocompromised, multiple ring-enchancing lesions bartonella Hanse lea= skin/soft tissue infection and lymphadenitis |
H infuenza | X (HEMATIN) AND V (NAD+), type B has PP polysaccharide |
What are the contact precautions for MDR organisms. Enteric and scabies? | hand hygiene, non sterile gloves, gowns, private room |
Organisms isolated from intraabdominal abscess? | B.fragilis, e.coli, enterococci and streptococci |
Why does N.gonorrhea has recurrent infection? | Presence of high antigenic variability of surface markers (Opa protiens, porins and LPO) |
B-hexosaminidase A deficiency and accumulation of GM2 ganglioside in lysosomes | Tay Sachs (a gang of six small jews), cherry red macula spot, Intellectual disability, seizures, hypotonia, macrocephaly |
yellow-white plaques on colonic mucosa with fibrin and inflammatory deposits. which events caused this? | (C.difficile infections) recent hospitalization and antibiotics for pneumonia (fluoroquinolone) |
Colitis associated VS sporadic colorectal cancer? | Colitis: young, flat lesion, late APC early P53, multifocal origin, proximal to distal (CROHN DZ), poor diff, mucinous Sporadic: older age, polypoid lesions, single focal, early APC and late P53, distal to proximal, well diff and not mucinous (rarely) |
Annular pancreas vs pancreas divisum? | annular pancreas: abnormal migration of ventral pancreatic bud during 7th and 8th week, duodenal obstruction or pancreatitis divisum: asymptomatic, failure of fusion of ventral and dorsal bud, associated with acute or chronic pancreatitis. |
Cardiac arrest+ loss of grey-white matter diff with sulcal effacement+ no pupillary response. lesion? | Upper midbrain (anoxic brain injury) contains optic nerve, oculomotor nerve, edinger westphal nuclei, pretectal nuclei. |
HLA -A/B/C class? | CLASS I , CD 8+ (EXPRESSED BY ALL NUCLEATED CELLS) |
what to do when patient is tremulous, agitated with elvated pulse and blood pressure? | give benzodiazepines (diazepam, lorazepam, chlordiazepoxide) |
hx of respo infxn and now muscle weakness in 32M | GBS- endoneurial inflammatory infiltration, ascending (from feet to legs)symmetric weakness, acute demyelinating polyneuropathy, usually receds respiratory or gastroenteritis illness |
risk for EBV? markers? | 50% B-cell lymphomas and most CNS lymphomas, t(8;14) over expression of c-myc, starry sky (benign macrophage) , Ki-67 high fraction |
Alzheimer's disease atrophy? | Hippocampal and temporoparietal |
enlarged lymph nodes peau d orange, edema, erythema, retracted nipple | inflammatory breast cx due to lymphatic obstruction |
21 hydroxylase deficiency? | SALT WASTING + HYPOTENSION dec. cortisol and aldosterone, inc. testosterone and 17-hydroxyprogesterone ambiguous genitalia in girls |
11 B-hydroxylase deficiency? | SALT RETENTION +HTN dec. cortisol and aldosterone, inc. testosterone and 11-deoxycortisone ambiguous genitalia in girls |
17 a hydroxylase deficiency? | SALT RETENTION + HTN dec. cortisol and aldosterone, inc. mineralocorticoids and corticosterone all patients are female |