Ch 74 bone mineralization drill
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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Side effect of calicium, Vit D products | constipation
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What class of drugs cause decreased absorption of Vit D and calcium products | corticosteroids
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Oral forms of calcium | Calcium salts usually calcium carbonate which has highest percentage of calcium, cheapest
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Other forms of calcium salts - Ca | chloride, gluconate, glucepate, lactate, acetate, citrate
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What is the oral form of calcium | calcium glubionate
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What is the inactive form of Vitamin D | cholecalciferol
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Which activated Vitamin D is given po or injection | calcitriol
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Which activated Vitamin D is given po only and synthetic | doxercalciferol
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Which activated Vitamin D is given injection only and is synthetic | paricalcitol
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What is the MOA of bisphosphonates | very poor bioavailability into bone where it decreases osteoclast activity
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Name 3 bisphosphonates | alendronate, risedronate, ibandronate
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Which bisphosphonates are given either daily or weekly | alendronate, risendronate
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Which bisphosphonate is given either daily or monthly | ibandronate
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What SERM is commonly used for osteoporosis and may also protect against estrogen-receptor-positive breast cancer | raloxifine
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What is the MOA of calcitonin | major role to inhibit osteoclasts--> decreased bone resorption
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What is calcitonin used for | only drug to TREAT (not prevent) osteoporosis
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What is an unusual ADR for some calcitonin long-term patients | they can develop antibodies to this product
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What is the only drug to increase bone formation | teriparatide
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How does teriparatide increase bone formation | it is a recombinant form of PTH. It increases osteoblast activity > osteoclast activity with net effect of increased bone formation
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What drug is a calcimemetic | cinacalet
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What is cinacalcet's MOA | increases sensitivity of calcium sensing cells in the parathyroid --> negative feedback to decrease PTH secretion at lower levels of Calcium than usual
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what is cinacalcet given for | hypercalcemia (keeps calcium on the bone by increasing PTH receptor sensitivity)
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Created by:
lorrelaws
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