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Ch 74 bone mineralization drill

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
        Help!  

Question
Answer
Side effect of calicium, Vit D products   constipation  
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What class of drugs cause decreased absorption of Vit D and calcium products   corticosteroids  
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Oral forms of calcium   Calcium salts usually calcium carbonate which has highest percentage of calcium, cheapest  
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Other forms of calcium salts - Ca   chloride, gluconate, glucepate, lactate, acetate, citrate  
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What is the oral form of calcium   calcium glubionate  
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What is the inactive form of Vitamin D   cholecalciferol  
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Which activated Vitamin D is given po or injection   calcitriol  
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Which activated Vitamin D is given po only and synthetic   doxercalciferol  
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Which activated Vitamin D is given injection only and is synthetic   paricalcitol  
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What is the MOA of bisphosphonates   very poor bioavailability into bone where it decreases osteoclast activity  
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Name 3 bisphosphonates   alendronate, risedronate, ibandronate  
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Which bisphosphonates are given either daily or weekly   alendronate, risendronate  
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Which bisphosphonate is given either daily or monthly   ibandronate  
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What SERM is commonly used for osteoporosis and may also protect against estrogen-receptor-positive breast cancer   raloxifine  
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What is the MOA of calcitonin   major role to inhibit osteoclasts--> decreased bone resorption  
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What is calcitonin used for   only drug to TREAT (not prevent) osteoporosis  
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What is an unusual ADR for some calcitonin long-term patients   they can develop antibodies to this product  
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What is the only drug to increase bone formation   teriparatide  
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How does teriparatide increase bone formation   it is a recombinant form of PTH. It increases osteoblast activity > osteoclast activity with net effect of increased bone formation  
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What drug is a calcimemetic   cinacalet  
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What is cinacalcet's MOA   increases sensitivity of calcium sensing cells in the parathyroid --> negative feedback to decrease PTH secretion at lower levels of Calcium than usual  
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what is cinacalcet given for   hypercalcemia (keeps calcium on the bone by increasing PTH receptor sensitivity)  
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Created by: lorrelaws
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