Busy. Please wait.
Log in with Clever
or

show password
Forgot Password?

Don't have an account?  Sign up 
Sign up using Clever
or

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Ch. 60 Est/Progest non-contraceptive

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
        Help!  

Question
Answer
General fx of estrogen/progesterone   *sexual organs/menstruation *bone/prevent resorption, maint density, *cholesterol favorable effects  
🗑
Estrogen given without progesterone can cause what adverse effects (first four)   *endometrial hyperplasia *ovarian ca *breast ca *stimulates existing ca using estrogen receptors  
🗑
Estrogen/progestin adverse effects (second four)   *CV increase MI, DVT, CVA, VTE *GI A, N, V *GB cholelithiasis  
🗑
Minor s/e of both est/progest   jaundice, HA, depr, Na/H20 retent  
🗑
Major non-contraceptive uses   *HRT *female hypogonadism *acne *prostate ca  
🗑
Routes of est/progest   po, transdermal, vag, parenteral  
🗑
SERMs definition   selective estrogen receptor modulator  
🗑
MOA of SERMs   mixed action - agonist and antagonist  
🗑
2 SERM drugs   *tamoxifen *raloxifene  
🗑
positive effects of both SERMs   *tx breast ca *prevent osteoporosis *positive lipid effects  
🗑
negative effects SERMs tamoxifen   *hot flashes *endometrial ca *VTE  
🗑
negative effect of SERM raloxifene   *hot flashes *VTE *DOES NOT cause endometrial hyperplasia  
🗑
General fx of endogenous progesterone   *prepare/maintain uterine lining (secretory changes in leutal phase) *cervical secretions - inc. visc, dec amt *maint pg, inhibit uterine contractions *some estrogenic, adrogenic, anabolic effects  
🗑
What might be given to prevent pre-term labor   progestins to inhibit uterine contractions  
🗑
first 4 ADRs of progestins   *teratogenic fetus masculinization *menstrual irreg (BTB, amenorr) *cervical secretions dec amt, inc visc *if used with estrogen-->breast ca  
🗑
second 3 ADRS of progestins   *breast tenderness *depression *same misc as estrogen (and phto sens, wt gain, dec app)  
🗑
Noncontraceptive tx uses of progestin   *HRT *uterine dx (bleed, amenorr, endometriosis, endometrial ca) *PMS  
🗑
how does progest effect uterine lining?   it makes endometrium thinner to prevent ca  
🗑
benefits of HRT   *dec vasomotor menop effects *dec uroginital dysfx, atrophy *dec bone loss *dec colon cancer *maybe QOL  
🗑
Is HRT established to provide a CV benefit?   No, HRT has NOT been established to provide a CV benefit  
🗑
Risks of HRT   *CV events *if ET only, not EPT: ovarian, uterine ca *breast ca *cholecystitis, lithiasis  
🗑
What do we give for HRT with in tact uterus   pempro given for this uterine status  
🗑
What do we give for HRT s/p hysterectomy?   premarin given for this uterine status  
🗑
Example of EPT drug   pempro representative of this class  
🗑
Example of ET drug   premarin representative of this class  
🗑
WHI, HERs study concenus   *HRT NOT advised >4 yrs (long term) *IS advised < 4 years  
🗑
WHI, HERs study short term uses   *vasomotor menop sxs *osteoporosis *vulvar/vaginal menop atrophy  
🗑


   

Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
 
To hide a column, click on the column name.
 
To hide the entire table, click on the "Hide All" button.
 
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
 
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.

 
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how
Created by: lorrelaws
Popular Nursing sets