Shaz book TQs
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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Window period for HIV NAT | 9 days
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Window period for HIV EIA | 21 days
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Window period for HCV MP NAT | 7 days
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Window period for HCV EIA | 51 to 58 days
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Window period for Hep B Surface Ag | 30-38 days
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Window period for HBV NAT | 40 to 50 days MP NAT; ID NAT 15-34 days
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Window period for HTLV test | 80
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Which transfusion transmitted agent is only tested for once in the lifetime of the donor? | T. cruzi, the agent for Chagas disease
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current estimate of risk of infection with HIV from blood transfusion | <1 in 2 million products
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What group and "clade" or subtype of HIV is most prevalent in the US? | Group M and clade B
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Window period for 3rd generation anti-HIV tests? | 22 days
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Window period for HIV NAT | 10 days
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False positive rate for anti-HIV EIA | 1 in 20K
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Reentry testing for an isolated reactive anti-HIV EIA donor can be performed after this time has elapsed | 8 weeks
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estimated risk of contracting hepatitis B from a transfusion in US | 1 in 250K
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required tests for hepatitis B for donated units of blood | anti-hepB core ab, HBV surface ag, HBV NAT
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window period for HBV NAT | 40 days
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Risk of transfusion transmitted HCV | 1 in 1.8 million units
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FDA regulations of HCV "lookbacks" require collection centers to notify consignees within how many days? | 30 days
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Deferral period for a donor who test positive for West Nile Virus by NAT | 120 days
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The first transfusion transmitted disease tested for in the USA | syphilis
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Why do most blood centers use treponemal tests for syphilis rather than non-treponemal tests (RPR)? | automation
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Current residual risk for HTLV infection from a blood transfusion | 1 in 2 million
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Diseases associated with HTLV1 infection | Adult T cell leukemia/lymphoma and tropical spastic paraperesis (HTLV1 associated myelopathy)
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Region where HTLV infection is endemic | Caribbean
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Proven disease associations with HTLV II | none
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T. cruzi is transmitted by this bug | triatomine bug
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Which transfusion transmitted disease test is only done once in a donor's lifetime? | T. cruzi antibody (Chaga's)
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Rate of septic transfusion reaction for apheresis platelets | 1 in 500K
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Source of contamination for majority of bacterially contaminated apheresis platelet units | skin (gram positive)
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Organisms most often implicated in septic transfusion reaction | gram negatives
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What malignancy has been reported in blood donors whose apheresis platelet units test culture positive for streptococcus bovis and streptococcus G? | colon cancer
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Verax test detects these | lipotechoic acid and lipopolysacchiride
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