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Shaz book TQs

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Window period for HIV NAT   9 days  
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Window period for HIV EIA   21 days  
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Window period for HCV MP NAT   7 days  
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Window period for HCV EIA   51 to 58 days  
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Window period for Hep B Surface Ag   30-38 days  
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Window period for HBV NAT   40 to 50 days MP NAT; ID NAT 15-34 days  
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Window period for HTLV test   80  
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Which transfusion transmitted agent is only tested for once in the lifetime of the donor?   T. cruzi, the agent for Chagas disease  
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current estimate of risk of infection with HIV from blood transfusion   <1 in 2 million products  
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What group and "clade" or subtype of HIV is most prevalent in the US?   Group M and clade B  
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Window period for 3rd generation anti-HIV tests?   22 days  
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Window period for HIV NAT   10 days  
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False positive rate for anti-HIV EIA   1 in 20K  
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Reentry testing for an isolated reactive anti-HIV EIA donor can be performed after this time has elapsed   8 weeks  
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estimated risk of contracting hepatitis B from a transfusion in US   1 in 250K  
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required tests for hepatitis B for donated units of blood   anti-hepB core ab, HBV surface ag, HBV NAT  
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window period for HBV NAT   40 days  
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Risk of transfusion transmitted HCV   1 in 1.8 million units  
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FDA regulations of HCV "lookbacks" require collection centers to notify consignees within how many days?   30 days  
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Deferral period for a donor who test positive for West Nile Virus by NAT   120 days  
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The first transfusion transmitted disease tested for in the USA   syphilis  
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Why do most blood centers use treponemal tests for syphilis rather than non-treponemal tests (RPR)?   automation  
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Current residual risk for HTLV infection from a blood transfusion   1 in 2 million  
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Diseases associated with HTLV1 infection   Adult T cell leukemia/lymphoma and tropical spastic paraperesis (HTLV1 associated myelopathy)  
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Region where HTLV infection is endemic   Caribbean  
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Proven disease associations with HTLV II   none  
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T. cruzi is transmitted by this bug   triatomine bug  
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Which transfusion transmitted disease test is only done once in a donor's lifetime?   T. cruzi antibody (Chaga's)  
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Rate of septic transfusion reaction for apheresis platelets   1 in 500K  
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Source of contamination for majority of bacterially contaminated apheresis platelet units   skin (gram positive)  
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Organisms most often implicated in septic transfusion reaction   gram negatives  
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What malignancy has been reported in blood donors whose apheresis platelet units test culture positive for streptococcus bovis and streptococcus G?   colon cancer  
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Verax test detects these   lipotechoic acid and lipopolysacchiride  
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