pharmacology drugs
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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Acetylcholine (ACh) | muscarinic and nicotinic agonist. | neurotransmitter
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Adrenaline | non-selective adrenoreceptor agonist. | cardiac arrest
anaphylaxis (allergic rxn)
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Atropine | non-selective muscarinic agonist | premedication before surgery
bardycardia (low BPM)
GI spasms
anticholinesterase poisoning
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Bethanecol | non-selective muscarinic agonist | urinary retension
constipation
-relaxes muscles
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Botox | exocytosis blocker selective cholinergic uptake | hyperhydrosis (increased sweating/perspiration)
muscle spasm
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Butoxamine | β2-adrenoceptor antagonist | experimental pharmacology
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Carbachol | (synthetic) muscarinic and nicotinic agonist | relaxes smooth muscle
eye/ophthalmic purposes like glaucoma
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Carbidopa | inhibitor of DOPA decarboxylase | Parkinsons
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Clonidine | partial α2-adrenoceptor agonist | hypertension (high BP)
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Darifenacin | M3-selective muscarinic antagonist | reduce urinary frequency
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Diclyomine | non-selective muscarinic antagonist | irritable bowel syndrome
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Distigmine | medium duration anticholinesterase | inhibits breakdown of ACh in synapse, so prolongs it's effecs on the postsynaptic receptors
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Dobutamine | β1-adrenoceptor agonist | cardiogenic shock
cardiac surgery
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Ecothiopate | irreversible anticholinesterase | glaucoma (eye drops - reduce intraocular pressure within eye)
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Ephedrine | indirectly acting sympathomimetic | nasal congestion - relaxes airways
stimulant - speeds up heart and nervous system
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Guanethidine | blocks NA realease | hypertensive crisis (high BP, impairing 1+ major organ system)
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Hemicholinium | presynaptic ACh uptake blocker | decreases production of ACh - so is an indirect ACh antagonist.
No clinical use - but used in research experiments
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Hyoscine | non-selective muscarinic antagonist | premedication before surgery
GI spasms
motion sickness
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Ipratropium | non-selective muscarinic antagonist | asthma - relaxes airways by inhibiting constriction of smooth muscles
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Isoprenaline | non-selective β-adrenoceptor agonist | shock
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Labetalol | non-selective α1, β1-2 antagonist | hypertension (high BP)
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Methyldopa | partial α2-adrenoceptor agonist precursor | hypertension (high BP) in pregnancy
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Muscarine | non-selective muscarinic agonist | favours rest and digest
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Neostigmine | medium duration anticholinesterase | constipation - contracts GI tract smooth muscles
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Nicotine | nicotinic AChR agonist |
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Noradrenaline (NA) | non-selective adrenoceptor agonist | neurotransmitter
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Oxotremorine | non-selective muscarinic agonist | experimental pharmacology
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Phenoxybenzamine | irreversible α-adrenoceptor antagonist | phaeochromocytoma (tumour at adrenal medulla - extra chromaffin tissue, so more NA/Adrenaline)
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Phentolamine | α-adrenoceptor antagonist | phaeochromocytoma (tumour at adrenal medulla - extra chromaffin tissue, so more NA/Adrenaline)
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Phenylephrine | α1-adrenoceptor agonist | nasal congestion
acute hypertension (high BP)
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Pilocarpine | non-selective muscarinic agonist | glaucoma
dry eyes
mouth
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Pirenzepine | M1-selective muscarinic antagonist | peptic ulcer
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Prazosin | α1-adrenoceptor antagonist | hypertension (high BP)
prostatic hyperplasia (enlarged prostate)
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Propanolol | non-selective β-adrenoceptor antagonist | hypertension (high BP)
anxiety
migraine
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Reserpine | vesicular monoamine uptake blocker | experimental
can cause depression/hypotension
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Salbutamol | β2-adrenoceptor agonist | asthma (short term)
premature labour
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Salmeterol | β2-adrenoceptor agonist | asthma prophylaxis
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Timolol | non-selective β-adrenoceptor antagonist | hypertension
angina
migraine
glaucoma
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Tropicamide | non-selective (but M4 prefering) muscarinic antagoninst | eye examinations
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Tyramine | amino acid responsible for cheese reaction |
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Vesamicol | vesicular ACh uptake blocker |
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Yohimbine | α2-adrenoceptor antagonist | aphrodisiac?
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α-Methyltyrosine | inhibitor of tyrosine kinase |
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Atenolol | β1-adrenoceptor antagonist. | hypertension (high BP)
angina (narrowing of coronal arteries)
arrhythima (irregular heart beat)
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