Mod 3 Lec 1
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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Is yeast an endogenous or exogenous infection? | Endogenous, opportunist
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Candida spp. can cause | Vulvo-vaginitis, thrush, pulmonary infections, eye infections, meningitis, endocaridtis, disseminated infections
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Thrush is a sign of _____ and is caused by_____. | Immunosuppression,Candida spp
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The most common cause of yeast infections is? | Candida albicans
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Candida albicans macro | Creamy
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Candida albicans micro | Clusters of blastoconidia along pseudohyphae, terminal chlamydoconidia
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Candida albicans germ tube test result | Positive
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Candida albicans is sucrose | Positive
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Candida stellatoidea is sucrose | Negative
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The second most common Candida spp. is? | Candida tropicalis
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Candida tropicalis can cause | Vaginitis, intestinal disease, systemic infections, meningitis
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Candida tropicalis infections are | aggressive and difficult to treat with traditional antifungals
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Candida tropicalis macro | Creamy, glabrous with mycelial fringe
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Candida tropicalis micro | Blastoconidia are single or small random clusters along pseudohyphae
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Candia parapsilosis is a major cause of what? | Nosocomial infections, related to indwelling catheters
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Candida parapsilosis micro | Creamy, glabrous
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Candida parapsilosis macro | Relatively short, crooked or curved pseudohyphae
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Candida kreusi can cause what? | Rarely isolated as a cause of endocarditis and vaginitis.
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Candida kreusi micro | Creamy, flat colonies
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Candida kreusi macro | Pseudohyphae and elongated blastoconidia, branch like trees
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Candida kefyr can cause what? | Endocarditis and UTI, one of the 4 most frequently isolated
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Candida kefyr micro | Creamy, smooth
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Candida kefyr macro | "logs in a stream" or "log jam"
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Candida guilliermondii can cause what? | UTI and endocarditis
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Candida guilliermondii macro | Creamy, flat, glossy
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Candida guilliermondii micro | Short pseudohyphae with groups of blastoconidia at constrictions
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Torulopsis glabrata is also called | Candida glabrata
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Torulopsis glabrata is most frequently found as | Fungemia, can also cause endocarditis, meningitis, UTI
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Torulopsis glabrata macro | Creamy, smooth, moist
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Torulopsis glabrata micro | Blastoconidia only (on CMT), no pseudohyphae
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The "working yeast" is? | Saccharomyces cerevisiae
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Saccharomyces cerevisiae is increasingly being isolated from? | Immunocompromised
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Saccharomyces cerevisiae macro | Creamy, smooth, moist
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Saccharomyces cerevisiae micro | Yeast cells and pseudohyphae
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Cryptococcus spp. is the causative agent of? | Meningitis and pulmonary disease
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Cryptococcus neoformans is found where? | Soil contaminated with pigeon droppings
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Cryptococcus neoformans is a major cause of what? | Opportunistic infections in AIDS patients, also meningitis-predilection for CNS
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What do all species of Cryptococcus spp. have? And what is used to detect this? | Capsule, India Ink (negative stain)
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What does Cryptococcus spp. look like on cornmeal agar? | Doesn't produce true or pseudohyphae, blastoconidia only
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What are the urease and nitrate results of Cryptococcus spp? | Ureast positive in all, nitrate variable
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What has a dark colony color on caffeic acid agar or bird seed agar? | C. neoformans, melanin production
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Rhodotorula spp is closely related to what? | Cryptococcus, has a capsule
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Rhodotorula spp urease and nitrate results | Urease positive, some are nitrate positive
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Rhodotorula spp. macro | Bright, salmon colored colonies
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Geotrichum candidum is normal flora where? | Intestinal tract
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Geotrichum candidum macro | White, moist, yeastlike
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Geotrichum candidim micro | True hyphae, segments into arthroconidia, no blastoconidia
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Trichosporon beigelii causes what? | White piedra, emerging agent of disseminated infection mainly in cancer patients.
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Trichosporon is resistant to what? | Amphotericin B
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Trichosporon beigelii micro | Produces arthroconidia and blastoconidia on cornmeal agar
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Malassezia furfur causes what? | Tinea versicolor and catheter related infections in patients on long term IV lipids.
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Malassezia furfur macro | Cream, brown, wrinkled
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Malassezia furfur micro | Yeastlike cells with collarettes
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Sporobolomyces spp. is mostly recovered from where? | Environmental samples
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Sporobolomyces spp. macro | Salmon colored smooth colonies
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Sporobolomyces spp. micro | Oval, elongate yeast cells, projectile spores
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Pneumocystis jiroveci is the new name for what? | Pneumocystis carinii
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What is undecided about Pneumocystis jiroveci? | Group, is it a yeast, protozoa, fungus
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Pneumocystis jiroveci causes what kinds of infections? | Opportunistic in AIDS patients, no cellular immunity
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What does Pneumocystis pneumonia do? | Destroys alveolar cells
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How can you diagnose Pneumocystis jiroveci in the lab? | Demonstrate organism in tissue, lavage, or sputum
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Can Pneumocystis jiroveci be cultured? | Only in animals
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What is a commonly used stain for Pneumocystis jiroveci? | GMS, looks like a "deflated ball"
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