Question | Answer |
Drug | any chemical that can affect living processes |
Pharmacology | study of drugs and their interactions |
Clinical Pharmacology | study of drugs in humans |
Pharmatherapeutics | use of drugs to diagnose, prevent or treat disease or to prevent pregnancy |
3 most important characteristics of any drug | effectiveness, safety, selectivity |
Reversible Action | For some, reversible in appropriate amount of time |
Predictability | no way to determine in advance |
Ease of administration | reduces errors in administration |
Chemical stability | drugs would retain their stability in both shelf life and in solutions |
Therapeutic Objective | provide maximum benefit with minimum harm |
Pharmacokinetics | how the drugs move into the body: absorption, distribution, metabolism, excretion |
Pharmacodynamics | impact of drugs on body once it has reached its site of action |
Five Rights | drug, patient, dose, route, time |
Individual Variation | factors in the individual person |
7 aspects of drug therapy | preadministration assessment, doseage and administration, evaluating and promoting therapeutic effects, minimizing adverse effects, making PRN decisions, managing toxicity |
High Risk Patients | liver, kidney dysfunction, genetic factors, drug allergies, pregnancy, elderly, infants |
Pharmacology and the Nursing Process | assessment, analysis and nursing diagnoses, planning, implementation, evaluation |
Baseline assessment data | interviewing, observation, phy. exam, lab tests, medical history, drug history |
Evaluation of drug therapy | therapeutic response; compare current with baseline, adverse drug reactions/interactions, compliance w/drug therapy, satisfaction with drug regimen |
Stages of new drug development | preclinical testing, clinical testing, randomized controlled trial |