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Components of cognitive remediation therapy Three components - assessment ; treatment to remediate impairments; cognitive mediation
Negative symptoms in schizophrenia alogia anhedonia affective flattening abulia social withdrawal and apathy
Components of family therapy in schizophrenia family psychoeducation build a therapeutic alliance with the family; address high EE; increase problem solving capacity of family
Principles of managing treatment resistant schizophrenia Establish true resistance - at least two failed treatment trials with two differenct antipsychotics; treat pseudoresistance
Clozapine side effects agranulocytosis - risk factors include afro-carribean ethnicity
Cardiovascular side effects of clozapine myocarditis-flu like symptoms
NMS fever; diaphoresis; rigidity; fluctuating consciousness; autonomic instability; fluctuating BP and tachycardia
Investigations increased CK; leucocytosis; altered liver function tests
Risk factors for NMS high potency typical drugs; abrupt withdrawal of anticholinergics; parkinsons disease; organic brain disease



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