| Question |
Answer |
| What are 2 determinants of GFR? | MAP, AFFERENT Arteriole diameter |
| How would increased Sympathetic activity affect GFR? | Increase Sympathetic --> Vasoconstriction --> DECREASE GFR --> decrease Urine Output |
| How would decreased Symapathetic activity affect GFR? | decrease Sympathetic --> Vasodilation --> INCREASE GFR --> increase Urine Output |
| What effect would Hemorage have on GFR and why? | decrease Pressure --> decrease GFR --> conserve H2O and restore Blood volume |
| How do Epinephrine and Renin affect GFR? | Vasoconstricting agents - constrict --> DECREASE GFR |
| Where does Epinephrine come from? | Adrenal Medulla |
| Where does Renin come from? | secreted by the cells of the Juxtaglomerular Complex |
| What effect do vasodilating agents have on GFR? give an example. | dilate --> ^ GFR --> ^ UO |
| What 3 factors influence Afferent Arteriole diameter? | relative Sympathetic activity, Vasoconstricting agents, Vasodilating agents |
| How does age affect GFR? | DECREASE GFR - because of Atherosclerosis |
| How are BP and GFR correlated? | ^ BP --> ^ GFR and decrease BP --> decrease GFR |
| How is GFR measured? | Liters filtered per day - average 93 mm Hg |
| Where does MAP affect GFR? | Global - from the whole body |
| Where doe Afferent Arteriole diameter affect GFR? | Local = best - affect GFR moment to moment |
