ceutics
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| most frequently dispensed dosage form in the US | tablets
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| tablets are prepared primarily by | compression
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| what addes the neccessary bulk to a formulation to prepare tablets of the desired size | diluents and Fillers
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| which promatoes adhesion of the particles of the formulation, allowing a granualtion to be prepared and maintaining the integrity of the final tablet | binders and adhesive
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| what promotes breakup of the tablets after adminsistration to smaller particles for ready drug availbility | disintegrants
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| what enhance the flow of the material into the tablet dies, minimize wear of the punches and dies, prevent fill material from sticking to the punches and dies, and produce tablets with sheen | antiadherents, glidants, lubricants or lubricating agents
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| prepared by subjecting the fill material to more than a single compression | multiply compressed tablets (def)
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| lyophilization | zydis technology R.P. Scherer Claritin
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| soft direct compression | wow-tab technology by yamomouchi Pharma Benadryl Fastmelt
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| mask taste in dissolving tablets by surrounding particles by a coat | micoroencapsulation and nanoencapsulation
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| QC meassure where by you take the avg. weight of 10 tablets | weight variation test
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| QC meassure where by you assay 10 dosage units and it must lie b/w 85%-115% SD of <6% | content uniformity test
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| QC meassure where by you measure tablets with vernier caliper, hand gauge, or automate equ. | tablet thickness test
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| QC meassure where by you meassure the amount of pressure applied to make the tablet | tablet hardness
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| QC meassure where by you rotate tablets and compare weight loss must not be >1% | tablet friability
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| QC meassure where you put the drug through cycles in immersion fluid and record time | tablet disintegration
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| QC meassure where by you look at scale up batches of 10% or 100,000 dosage units whichever greater and predict IVIVC correlation solubility and permeability | tablet dissolution
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