Gametogenesis-Test #1
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| Embryology | The formation of basic structures of the body; 2nd-8th week
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| Development | Maturation using basic plan est. during embryogenesis; incl. pre- & post- natal periods
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| Teratology | Study of causes of birth defects
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| Gametogenesis | Production of the 2 cells required for generation of new individual
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| What is the purpose of Meiosis? | 1. To reduce chromosome # by 1/2 2. Two cell divisions w/ 1 round of DNA replication 3. 1st division reduces chromosomes from 46 (diploid) to 23 (haploid)
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| Primary germ cells divide by what? | Meiosis
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| How many gametes are produced by 1° spermatocyte (males)? | 4 gametes
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| How many gametes are produced by 1° ooctye (females)? | 1 gamete
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| Spermatogenesis | Process of prod. of male gamete & modifying it to perform reprod. function
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| Purpose of Spermatogenesis? | 1. Takes place in SEMINIFEROUS TUBULES 2. Begins at puberty & continues throughout life 3. 1° spermatocytes by meiosis I produce 2° spermatocytes; 2nd meiotic division 2° spermatocytes=2 spermatids 4. Undergo spermiogenesis
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| Spermiogenesis | Converts immature spermatids to mature spermatozoan
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| Process of Spermiogenesis | 1. Spermatids lose most of their cytoplasm 2. Nucleus condenses 3. Acrosome forms which contains the enzymes needed for fertilization 4. Flagellum develops, necessary for motility 5. Process takes 64 days
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| Oogenesis | Formation of the female gamete
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| Process of Oognesis | 1. Takes place in ovary 2. Process begins during prenatal develop. 3. Oogonia divide by meiosis I to produce 1° oocytes and replicate DNA 4. By birth 1° oocytes surrounded by sngl layer of follicular cells and stopped at Meiosis I
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| Primary germ cells (1° ooctyes) in females are produced prior to when? | Prior to birth
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| 1° ooctyes | Remain dormant till puberty (10-14 yrs) and OMI Oocyte Maturation Inhibitor released by follicular cell; at puberty 1 oocyte/month matures and is released from ovary; 2nd Meiotic division only completed if FERTILIZATION takes place
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| Oogenesis & Spermatogenesis BOTH: | Produce haploid (23) gametes & Produce MATURE gametes beginning puberty
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| Diff. in oogenesis & spermatogenesis | Oogenesis: 1.No stem cell in ovary after birth 2. 1°ooctye=1 mature gamete 3. Large, nonmotile 4. 1 mature gamete prod./month 5.Prod. only till ~50 SPERMATOGENESIS: 1.Spermatogonia present AFTER birth 2. 1°sprmatocyte=4 gametes 3.Small;motile lots prod
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| Types of abnormal gametes | Chromosomal & Morphological
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| Types of Abnormal Chromosomal Gametes | Nondisjunction (Trisomy, Monosomy); Translocations; Deletions
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| Nondisjunction | A chromosomal anomaly that happens when chromosomes don't separate as they normally should. Two Types: Trisomy-3 copies of chromosomes; Monosomy-1 copy of a particular chromosome
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| Translocations | Chromosomes are damaged & repaired but repaired incorrectly
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| Deletions | Large or small segment of chromosomes is lost
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| Types of Morphological anomalies | Sperm: two heads or tails; nonmotile Oocytes: 2 oocytes in 1 follicle; 1 ooctye w/ more than one nucleus (binucleate)
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