Virus pt I
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| viruses that only replicate inside the host cell, cannot survive long term outside host cell | Obligate intracellular parasite
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| central genome of RNA/DNA and protein capsule shell, some have outer envelope; this is known as | Virion Design
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| Gold standard for ID/isolation of virus | Viral Culture
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| If specimen must be held over the weekend, what is optimal storage? | in transport medium, at temp that inhibits cellular degradation/microflora proliferation
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| 59 y/o transplant pt, on steroids for episodes of acute rejection, malaise, fatigue, feer, dyspnea, anemia/leukemia, what is likely problem? | CMV-Cytomegalovirus, an opportunistic infection
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| viral induced cell morphologic change, cytopathic effects, inclusion bodies, enlargement of the cell | CMV
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| cause of acute infection followed by latent infection with periodic reactivation and shedding of infectious virus | Herpesvirus
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| herpesviruses infecting epithelial cells, produce latent infections in neurons | Alpha group: HSV 1,2, VZV
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| group, CMV infects and produces latent infection in variety of cell types | lymphotrophic beta group
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| group with EBV, KSHV/HHV-8 that causes Kaposi sarcoma, latent infection in lymphoid cells | gamma group
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| often caused by HSV-2 than by HSV-1; vesicles on genital mucous membranes and external genitalia rapidly converted to superficial ulcerations irmmed by inflamm infiltrate | Genital herpes
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| routine cytology evaluating prepared viral smears | Tzanck Smear cytology
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| mutlinucleated giant cell observed in Tzanck prep with intranuclear unclusion | cytopathic effect
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emtdan85
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