ECC Test 3 Imm Mod.
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Interferons | Tx of Leukemias, Kaposi Sarcoma, Warts, Hep B and Malignant Melanoma. Naturally released from human cells in response to a viral invasion. Enhance inflammatory response.
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| Interleukins | Tx of renal carcinomas, AIDS, ARC. Chemicals produced by T-cells and used to communicate between lymphocytes, stimulate cellular immunity, and inhibit tumor growth.
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| Immune Suppressants | Used with corticosteroids. Block inflammatory response. Tx of organ transplant and in tx of autoimmune diseases (RA, Psoriasis)
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| Immune Stimulants-Prototype | Interferon Alfa-2b
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| Interferon Alfa-2b | Used for hairy cell leukemia, malignant melanoma, AIDS, Chronic Hep B&C. Inhibits growth of tumor cells and enhances immune response. Adverse: Flu-like symptoms.
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| Interleukins-Prototype | Aldesleukin (Proleukin)
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| Aldesleukin (Proleukin) | Produced by E.Coli. Tx of metastatic renal cell carcinoma in adults, metastatic melanomas, AIDS and ARC. Activates human cellularimmunity and inhibits tumore growth. Adverse: Flu-like symptoms, CNS.
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| T-and B-Cell Suppressors-Prototype | Cyclosporine (Sandimmune)
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| Cyclosporine (Sandimmune) | Suppression of rejection in variety of transplants, Rheumatoid arthritis, psoriasis.
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| Monoclonal Antibodies-Prototype | Muromonab (Orthoclone OKT3)
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| Muromonab (Orthoclone OKT3) | IV onset in mins, peak 2-7 days. Lasts 7 days. Used for tx of renal, cardiac and hepatic transplant pts. Adverse: Flu-like symptoms, acute pulmonary edema, increase susceptibility to infection.
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