ECC Test 3 Imm Mod.
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| Interferons | Tx of Leukemias, Kaposi Sarcoma, Warts, Hep B and Malignant Melanoma. Naturally released from human cells in response to a viral invasion. Enhance inflammatory response. | ||||
| Interleukins | Tx of renal carcinomas, AIDS, ARC. Chemicals produced by T-cells and used to communicate between lymphocytes, stimulate cellular immunity, and inhibit tumor growth. | ||||
| Immune Suppressants | Used with corticosteroids. Block inflammatory response. Tx of organ transplant and in tx of autoimmune diseases (RA, Psoriasis) | ||||
| Immune Stimulants-Prototype | Interferon Alfa-2b | ||||
| Interferon Alfa-2b | Used for hairy cell leukemia, malignant melanoma, AIDS, Chronic Hep B&C. Inhibits growth of tumor cells and enhances immune response. Adverse: Flu-like symptoms. | ||||
| Interleukins-Prototype | Aldesleukin (Proleukin) | ||||
| Aldesleukin (Proleukin) | Produced by E.Coli. Tx of metastatic renal cell carcinoma in adults, metastatic melanomas, AIDS and ARC. Activates human cellularimmunity and inhibits tumore growth. Adverse: Flu-like symptoms, CNS. | ||||
| T-and B-Cell Suppressors-Prototype | Cyclosporine (Sandimmune) | ||||
| Cyclosporine (Sandimmune) | Suppression of rejection in variety of transplants, Rheumatoid arthritis, psoriasis. | ||||
| Monoclonal Antibodies-Prototype | Muromonab (Orthoclone OKT3) | ||||
| Muromonab (Orthoclone OKT3) | IV onset in mins, peak 2-7 days. Lasts 7 days. Used for tx of renal, cardiac and hepatic transplant pts. Adverse: Flu-like symptoms, acute pulmonary edema, increase susceptibility to infection. |
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Created by:
Hughesj29
on 2012-04-25