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ECC Test 3 Imm Mod.

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Question
Answer
Interferons   Tx of Leukemias, Kaposi Sarcoma, Warts, Hep B and Malignant Melanoma. Naturally released from human cells in response to a viral invasion. Enhance inflammatory response.  
Interleukins   Tx of renal carcinomas, AIDS, ARC. Chemicals produced by T-cells and used to communicate between lymphocytes, stimulate cellular immunity, and inhibit tumor growth.  
Immune Suppressants   Used with corticosteroids. Block inflammatory response. Tx of organ transplant and in tx of autoimmune diseases (RA, Psoriasis)  
Immune Stimulants-Prototype   Interferon Alfa-2b  
Interferon Alfa-2b   Used for hairy cell leukemia, malignant melanoma, AIDS, Chronic Hep B&C. Inhibits growth of tumor cells and enhances immune response. Adverse: Flu-like symptoms.  
Interleukins-Prototype   Aldesleukin (Proleukin)  
Aldesleukin (Proleukin)   Produced by E.Coli. Tx of metastatic renal cell carcinoma in adults, metastatic melanomas, AIDS and ARC. Activates human cellularimmunity and inhibits tumore growth. Adverse: Flu-like symptoms, CNS.  
T-and B-Cell Suppressors-Prototype   Cyclosporine (Sandimmune)  
Cyclosporine (Sandimmune)   Suppression of rejection in variety of transplants, Rheumatoid arthritis, psoriasis.  
Monoclonal Antibodies-Prototype   Muromonab (Orthoclone OKT3)  
Muromonab (Orthoclone OKT3)   IV onset in mins, peak 2-7 days. Lasts 7 days. Used for tx of renal, cardiac and hepatic transplant pts. Adverse: Flu-like symptoms, acute pulmonary edema, increase susceptibility to infection.  


   


 

 

 
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Created by: Hughesj29 on 2012-04-25




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