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Drugs r/t BPH and Erectile Dysfunction

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Question
Answer
What is the result of PDE5 inhibition?   A long and harder erection.  
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Which drug is used for erectile dysfunction and pulmonary HTN?   Viagra (sildenafil)  
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Persistent and painful erection of the penis. Also an AE of Viagra.   Priapism  
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Name two rare AE of the Viagra.   Nonarteritic ischemic optic neruopathy. Sudden hearing loss.  
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Pts taking viagra should not stand up quickly. T or F?   True. Hypotension is a SE  
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Headache and flushing are potential AE of which erectile dysfunction drug?   Viagra (sildenafil)  
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Which of these drugs is not contraindicated with Viagra? Nitrites, Diuretics, a-blockers, CYP3A4 drugs?   Diuretics. The other three are contraindicated.  
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Cialis should only be taken when a pt has the need for an erection. T or F?   False. Take daily.  
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Which erectile dysfunction drug causes QT interval prolongation w/antidysrhythmic drugs? Viagra, Levitra, Cialis, or Avodart?   Levitra  
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Excessive growth of epithelial (gradular) cells is which type of BPH? Mechanical or Dynamic?   Mechanical  
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Exessive growth of smooth muscle cells is which type of BPH? Mechanical or Dynamic?   Dynamic  
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This type of BPH can have s/s without an enlarged prostate. Mechanical or Dynamic   Dynamic  
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5-alpha reductase inhibitors are used for which type of BPH? Mechanical or Dynamic?   Mechanical  
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Alpha-1 adrenergic antagonists are used for which type of BPH? Mechanical or Dynamic?   Dynamic  
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finasteride (Proscar) and dutasteride (Avodart) are used for which type of BPH? Mechanical or Dynamic?   Mechanical  
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Proscar and Avodart are known as which classification of drug?   5-alpha reductase inhibitors  
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Pt states they have been on Avodart for 4 months now and still have s/s of BPH. How should the nurse respond?   It may take 6-12 months to experience full effects.  
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Which lab levels should be drawn when taking Proscar? Should they be lower or higher than before drug started?   PSA. They should be lower.  
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Might pts who are on Proscar need a prescription for an erectile dysfunction as well? Why or why not?   Yes. An AE of Proscar/Avodart is dec. ejaculate vol. and libido.  
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A male pt on Avodart complains of pain, swelling, and growth in his pectoral area. How should the nurse respond?   Gynecomastia is an AE of Avodart  
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Women should avoid sexual intercourse with men taking Avodart if they are of child bearing age or pregnant? T or F?   True. Avodart is Preg X drug.  
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This BPH drug relaxes smooth muscle in the bladder neck, prostate capsule and prostatic urethra.   Alpha 1 Adrenergic Antagonists (Flomax)  
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This BPH drug is useful in symptom management with MILD enlargement   A-1 Adrenergic Ant.  
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silodosin (Rapaflo) and tamsulsosin (Flomax) are selective or nonselective?   Selective  
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Abnormal ejaculation is more an AE of selective or nonselective drugs?   Selective  
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"osins" such as alfuzosin are selective or nonselective drugs?   Nonselective  
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What is a primary nsg dx for "osin" drugs? Risk for infection, Risk for falls, Risk for disturbed body image, Risk for aspiration?   Risk for falls. AE of osins include Hypotension, dizziness, and fainting.  
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Nasal congestion is a common AE of selective or nonselective drugs?   Nonselective  
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Which of these drugs is most contraindicated with doxazosin? lasix, metformin, insulin, gabapentin?   Lasix. These two drugs combined can severly drop blood pressure.  
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What is an herbal preparation commonly used with BPH?   Saw Palmetto  
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Since Saw Palmetto is a herbal supplement, it is safe in use with pregnancy. T or F?   False  
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